Developmental impairments of craniofacial bone and cartilage in transgenic mice expressing FGF10

Developmental impairments of craniofacial bone and cartilage in transgenic mice expressing FGF10

Mutations in a common extracellular domain of fibroblast growth factor receptor (FGFR)-2 isoforms (type IIIb and IIIc) cause craniosynostosis syndrome and chondrodysplasia syndrome. FGF10, a major ligand for FGFR2-IIIb and FGFR1-IIIb, is a key participant in the epithelial-mesenchymal interactions r...

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Bibliographic Details
Main Authors: Hirotaka Yoshioka, Kazuko Kagawa, Tomoko Minamizaki, Masashi Nakano, Jane E. Aubin, Katsuyuki Kozai, Kazuhiro Tsuga, Yuji Yoshiko
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Bone Reports
Subjects:
FGF10
FGFR2
Craniofacial skeleton
Chondrogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187223000402

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