Preclinical Pharmacology of BA-TPQ, a Novel Synthetic Iminoquinone Anticancer Agent

Preclinical Pharmacology of BA-TPQ, a Novel Synthetic Iminoquinone Anticancer Agent

Marine natural products and their synthetic derivatives represent a major source of novel candidate anti-cancer compounds. We have recently tested the anti-cancer activity of more than forty novel compounds based on an iminoquinone makaluvamine scaffold, and have found that many of the compounds exe...

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Bibliographic Details
Main Authors: Ruiwen Zhang, Wei Wang, Sadanandan E. Velu, Xinyi Yang, Charnell I. Sommers, Elizabeth R. Rayburn, Xu Zhang, Evrim Gurpinar, Hongxia Xu, Xiangrong Zhang, Scharri J. Ezell, Haibo Li
Format: Article
Language:English
Published: MDPI AG 2010-07-01
Series:Marine Drugs
Subjects:
marine alkaloid
pharmacokinetics
protein binding
chemotherapy
Online Access:http://www.mdpi.com/1660-3397/8/7/2129/

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