Effects of Dose Amount for Antiepileptic Drugs on Lipid Profile of Male Rats (Rattus Norvegicus).
The present study aimd to estimate the changes in lipid profile depend on dosage amount of two AEDs ,Phenytoin (PHT) and Carbamazepine (CBZ) , and make a comparison between them in rats. A 30 healthy male Wistar rats (150-200 g) ( subdivide to five groups ) first group was control , the secon...
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| Format: | Article |
| Language: | English |
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University of Thi-Qar
2019-04-01
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| Series: | مجلة علوم ذي قار |
| Subjects: | |
| Online Access: | https://www.jsci.utq.edu.iq/index.php/main/article/view/18 |
| _version_ | 1797595824048308224 |
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| author | Abbas Mohsin Abbas |
| author_facet | Abbas Mohsin Abbas |
| author_sort | Abbas Mohsin Abbas |
| collection | DOAJ |
| description | The present study aimd to estimate the changes in lipid profile depend on dosage amount of two AEDs ,Phenytoin (PHT) and Carbamazepine (CBZ) , and make a comparison between them in rats. A 30 healthy male Wistar rats (150-200 g) ( subdivide to five groups ) first group was control , the second and third groups received (50 mg\kg and 100 mg\kg) of Phenytoin respectively, fourth and fifth groups received (25 mg/kg and 50 mg/kg) of Carbamazepine respectively. Serum total cholesterol (TC), triglycerides (TGs) and High-density lipoprotein (HDL) levels were measured after 20 days period of treating, Low-density lipoprotein (LDL) and Very low-density lipoprotein (VLDL) was calculated also. Our data revealed that, the administration of PHT (50 mg\kg) and CBZ (25 mg\kg) didn |
| first_indexed | 2024-03-11T02:42:54Z |
| format | Article |
| id | doaj.art-93e109e13d3440e495b0d5b7faa5cd6b |
| institution | Directory Open Access Journal |
| issn | 1991-8690 2709-0256 |
| language | English |
| last_indexed | 2024-03-11T02:42:54Z |
| publishDate | 2019-04-01 |
| publisher | University of Thi-Qar |
| record_format | Article |
| series | مجلة علوم ذي قار |
| spelling | doaj.art-93e109e13d3440e495b0d5b7faa5cd6b2023-11-18T09:30:29ZengUniversity of Thi-Qarمجلة علوم ذي قار1991-86902709-02562019-04-0162Effects of Dose Amount for Antiepileptic Drugs on Lipid Profile of Male Rats (Rattus Norvegicus).Abbas Mohsin Abbas0Chemistry department / College of science / Thi-Qar University The present study aimd to estimate the changes in lipid profile depend on dosage amount of two AEDs ,Phenytoin (PHT) and Carbamazepine (CBZ) , and make a comparison between them in rats. A 30 healthy male Wistar rats (150-200 g) ( subdivide to five groups ) first group was control , the second and third groups received (50 mg\kg and 100 mg\kg) of Phenytoin respectively, fourth and fifth groups received (25 mg/kg and 50 mg/kg) of Carbamazepine respectively. Serum total cholesterol (TC), triglycerides (TGs) and High-density lipoprotein (HDL) levels were measured after 20 days period of treating, Low-density lipoprotein (LDL) and Very low-density lipoprotein (VLDL) was calculated also. Our data revealed that, the administration of PHT (50 mg\kg) and CBZ (25 mg\kg) didnhttps://www.jsci.utq.edu.iq/index.php/main/article/view/18AEDsCBZPHTlipid profileCholesterolTGs |
| spellingShingle | Abbas Mohsin Abbas Effects of Dose Amount for Antiepileptic Drugs on Lipid Profile of Male Rats (Rattus Norvegicus). مجلة علوم ذي قار AEDs CBZ PHT lipid profile Cholesterol TGs |
| title | Effects of Dose Amount for Antiepileptic Drugs on Lipid Profile of Male Rats (Rattus Norvegicus). |
| title_full | Effects of Dose Amount for Antiepileptic Drugs on Lipid Profile of Male Rats (Rattus Norvegicus). |
| title_fullStr | Effects of Dose Amount for Antiepileptic Drugs on Lipid Profile of Male Rats (Rattus Norvegicus). |
| title_full_unstemmed | Effects of Dose Amount for Antiepileptic Drugs on Lipid Profile of Male Rats (Rattus Norvegicus). |
| title_short | Effects of Dose Amount for Antiepileptic Drugs on Lipid Profile of Male Rats (Rattus Norvegicus). |
| title_sort | effects of dose amount for antiepileptic drugs on lipid profile of male rats rattus norvegicus |
| topic | AEDs CBZ PHT lipid profile Cholesterol TGs |
| url | https://www.jsci.utq.edu.iq/index.php/main/article/view/18 |
| work_keys_str_mv | AT abbasmohsinabbas effectsofdoseamountforantiepilepticdrugsonlipidprofileofmaleratsrattusnorvegicus |