Case Report: Optic Disc Melanocytoma with PHOMS—Minimum Intensity Projection Image
Fubin Wang Department of Ophthalmology, Shanghai Bright Eye Hospital, Shanghai, 200336, People’s Republic of ChinaCorrespondence: Fubin Wang, Shanghai Bright Eye Hospital, 899 Maotai Road, Changning District, Shanghai, 200336, People’s Republic of China, Email wfb_528@163.comIntroduction: Optic disc...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2024-02-01
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| Series: | International Medical Case Reports Journal |
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| Online Access: | https://www.dovepress.com/case-report-optic-disc-melanocytoma-with-phomsminimum-intensity-projec-peer-reviewed-fulltext-article-IMCRJ |
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| author | Wang F |
| author_facet | Wang F |
| author_sort | Wang F |
| collection | DOAJ |
| description | Fubin Wang Department of Ophthalmology, Shanghai Bright Eye Hospital, Shanghai, 200336, People’s Republic of ChinaCorrespondence: Fubin Wang, Shanghai Bright Eye Hospital, 899 Maotai Road, Changning District, Shanghai, 200336, People’s Republic of China, Email wfb_528@163.comIntroduction: Optic disc melanocytoma (ODMC) with peripapillary hyperreflective ovoid mass-like structures (PHOMS) is rare. This study reports a case of the characteristics of multimodal imaging and Minimum intensity projection (Min-IP) images.Methods: A 25-year-old male patient was referred to our hospital due to the presence of a dark pigmented tumor located in the optic disc area of his left eye. The patient exhibited normal pupillary reactions and had a best corrected visual acuity of 1.0 (decimal) in both eyes. This patient underwent multimodal retinal imaging examination including color fundus photograph (CFP), B-scan ultrasonography, Fundus autofluorescence (FAF), SD-OCT (spectral-domain optical coherence tomography), OCTA (optical coherence tomography angiography), en-face Min-IP image and fluorescein angiography (FA).Results: CFP revealed a slightly elevated mass lesion in the inferior quadrant of the left optic disc, the lesion appeared black to dark brown in color. B-scan ultrasonography of the left eye confirmed the presence of a hyperechoic small dome-shaped lesion. Fundus autofluorescence (FAF) analysis revealed complete hypofluorescence in this area. SD-OCT (spectral-domain optical coherence tomography) and OCTA (optical coherence tomography angiography) with Min-IP were performed over the tumor and its surrounding areas. SD-OCT showed an elevated tumor mass arising from the optic disc with increased reflectivity. PHOMS appeared ovoid in shape on B-scan OCT image. PHOMS appeared peripapillary hyperreflective bright areas on en-face Min-IP image corresponding to PHOMS on B-scan OCT image. The fluorescein angiography (FA) showed the staining of PHOMS. A diagnosis of optic disc melanocytoma with PHOMS was established prompting the patient to be advised for regular follow-up.Conclusion: The optic disc melanocytoma with PHOMS is a rare benign ocular lesion that requires minimal active intervention, but demands a lifetime follow-up. The multimodal imaging and Min-IP images have clinical diagnostic value.Keywords: optic disc melanocytoma, peripapillary hyperreflective ovoid mass-like structures, minimum intensity projection, OCT, multimodal imaging |
| first_indexed | 2024-03-07T23:29:47Z |
| format | Article |
| id | doaj.art-93e4518e548342cca21d587b68d808c7 |
| institution | Directory Open Access Journal |
| issn | 1179-142X |
| language | English |
| last_indexed | 2024-03-07T23:29:47Z |
| publishDate | 2024-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Medical Case Reports Journal |
| spelling | doaj.art-93e4518e548342cca21d587b68d808c72024-02-20T17:10:12ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2024-02-01Volume 1713714190536Case Report: Optic Disc Melanocytoma with PHOMS—Minimum Intensity Projection ImageWang FFubin Wang Department of Ophthalmology, Shanghai Bright Eye Hospital, Shanghai, 200336, People’s Republic of ChinaCorrespondence: Fubin Wang, Shanghai Bright Eye Hospital, 899 Maotai Road, Changning District, Shanghai, 200336, People’s Republic of China, Email wfb_528@163.comIntroduction: Optic disc melanocytoma (ODMC) with peripapillary hyperreflective ovoid mass-like structures (PHOMS) is rare. This study reports a case of the characteristics of multimodal imaging and Minimum intensity projection (Min-IP) images.Methods: A 25-year-old male patient was referred to our hospital due to the presence of a dark pigmented tumor located in the optic disc area of his left eye. The patient exhibited normal pupillary reactions and had a best corrected visual acuity of 1.0 (decimal) in both eyes. This patient underwent multimodal retinal imaging examination including color fundus photograph (CFP), B-scan ultrasonography, Fundus autofluorescence (FAF), SD-OCT (spectral-domain optical coherence tomography), OCTA (optical coherence tomography angiography), en-face Min-IP image and fluorescein angiography (FA).Results: CFP revealed a slightly elevated mass lesion in the inferior quadrant of the left optic disc, the lesion appeared black to dark brown in color. B-scan ultrasonography of the left eye confirmed the presence of a hyperechoic small dome-shaped lesion. Fundus autofluorescence (FAF) analysis revealed complete hypofluorescence in this area. SD-OCT (spectral-domain optical coherence tomography) and OCTA (optical coherence tomography angiography) with Min-IP were performed over the tumor and its surrounding areas. SD-OCT showed an elevated tumor mass arising from the optic disc with increased reflectivity. PHOMS appeared ovoid in shape on B-scan OCT image. PHOMS appeared peripapillary hyperreflective bright areas on en-face Min-IP image corresponding to PHOMS on B-scan OCT image. The fluorescein angiography (FA) showed the staining of PHOMS. A diagnosis of optic disc melanocytoma with PHOMS was established prompting the patient to be advised for regular follow-up.Conclusion: The optic disc melanocytoma with PHOMS is a rare benign ocular lesion that requires minimal active intervention, but demands a lifetime follow-up. The multimodal imaging and Min-IP images have clinical diagnostic value.Keywords: optic disc melanocytoma, peripapillary hyperreflective ovoid mass-like structures, minimum intensity projection, OCT, multimodal imaginghttps://www.dovepress.com/case-report-optic-disc-melanocytoma-with-phomsminimum-intensity-projec-peer-reviewed-fulltext-article-IMCRJoptic disc melanocytomaperipapillary hyperreflective ovoid mass-like structuresminimum intensity projectionoctmultimodal imaging |
| spellingShingle | Wang F Case Report: Optic Disc Melanocytoma with PHOMS—Minimum Intensity Projection Image International Medical Case Reports Journal optic disc melanocytoma peripapillary hyperreflective ovoid mass-like structures minimum intensity projection oct multimodal imaging |
| title | Case Report: Optic Disc Melanocytoma with PHOMS—Minimum Intensity Projection Image |
| title_full | Case Report: Optic Disc Melanocytoma with PHOMS—Minimum Intensity Projection Image |
| title_fullStr | Case Report: Optic Disc Melanocytoma with PHOMS—Minimum Intensity Projection Image |
| title_full_unstemmed | Case Report: Optic Disc Melanocytoma with PHOMS—Minimum Intensity Projection Image |
| title_short | Case Report: Optic Disc Melanocytoma with PHOMS—Minimum Intensity Projection Image |
| title_sort | case report optic disc melanocytoma with phoms mdash minimum intensity projection image |
| topic | optic disc melanocytoma peripapillary hyperreflective ovoid mass-like structures minimum intensity projection oct multimodal imaging |
| url | https://www.dovepress.com/case-report-optic-disc-melanocytoma-with-phomsminimum-intensity-projec-peer-reviewed-fulltext-article-IMCRJ |
| work_keys_str_mv | AT wangf casereportopticdiscmelanocytomawithphomsmdashminimumintensityprojectionimage |