Baicalin Enhances Chemosensitivity to Doxorubicin in Breast Cancer Cells via Upregulation of Oxidative Stress-Mediated Mitochondria-Dependent Apoptosis

Baicalin Enhances Chemosensitivity to Doxorubicin in Breast Cancer Cells via Upregulation of Oxidative Stress-Mediated Mitochondria-Dependent Apoptosis

Doxorubicin (Dox) is an effective anthracycline anticancer drug. However, recent studies have revealed that Dox resistance is a highly critical issue, and a significant reason for treatment failure. Baicalin is a flavonoid component in the roots of <i>Scutellaria baicalensis</i> Georgi;...

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Bibliographic Details
Main Authors: Mei-Yi Lin, Wan-Ting Cheng, Hui-Ching Cheng, Wan-Ching Chou, Hsiu-I Chen, Hsiu-Chung Ou, Kun-Ling Tsai
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antioxidants
Subjects:
doxorubicin
baicalin
chemosensitivity
ROS
apoptosis
Online Access:https://www.mdpi.com/2076-3921/10/10/1506

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