Lactoferrin Induces Erythropoietin Synthesis and Rescues Cognitive Functions in the Offspring of Rats Subjected to Prenatal Hypoxia

Lactoferrin Induces Erythropoietin Synthesis and Rescues Cognitive Functions in the Offspring of Rats Subjected to Prenatal Hypoxia

The protective effects of recombinant human lactoferrin rhLF (branded “CAPRABEL™”) on the cognitive functions of rat offspring subjected to prenatal hypoxia (7% O<sub>2</sub>, 3 h, 14th day of gestation) have been analyzed. About 90% of rhLF in CAPRABEL was iron-free (apo-LF). Rat dams r...

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Bibliographic Details
Main Authors: Alexey V. Sokolov, Nadezhda M. Dubrovskaya, Valeria A. Kostevich, Dmitrii S. Vasilev, Irina V. Voynova, Elena T. Zakharova, Olga L. Runova, Igor V. Semak, Alexander I. Budevich, Natalia N. Nalivaeva, Vadim B. Vasilyev
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Nutrients
Subjects:
hypoxia
pregnancy
cognitive functions
lactoferrin
hypoxia-inducible factor
erythropoietin
Online Access:https://www.mdpi.com/2072-6643/14/7/1399

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