A Single Tertiary Center Outcomes on Cannulation Strategies and Extracorporeal Membrane Oxygenation in the Treatment of Respiratory Failure During COVID- 19 Infection
Aim:Extracorporeal membrane oxygenation (ECMO) is an important option for the management of severe acute respiratory distress syndrome (ARDS) in Coronavirus disease-2019 (COVID-19) cases. We aimed to present our experiences of ECMO in patients with respiratory failure secondary to COVID-19.Methods:D...
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| Format: | Article |
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Galenos Yayinevi
2021-06-01
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| Series: | Haseki Tıp Bülteni |
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http://www.hasekidergisi.com/archives/archive-detail/article-preview/a-single-tertiary-center-outcomes-on-cannulation-s/48061
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| author | Mustafa Ozer Ulukan Atalay Karakaya Yahya Yildiz Didem Melis Oztas Nurdan Kamilcelebi Servet Ozdemir Murat Ugurlucan Korhan Erkanlı |
| author_facet | Mustafa Ozer Ulukan Atalay Karakaya Yahya Yildiz Didem Melis Oztas Nurdan Kamilcelebi Servet Ozdemir Murat Ugurlucan Korhan Erkanlı |
| author_sort | Mustafa Ozer Ulukan |
| collection | DOAJ |
| description | Aim:Extracorporeal membrane oxygenation (ECMO) is an important option for the management of severe acute respiratory distress syndrome (ARDS) in Coronavirus disease-2019 (COVID-19) cases. We aimed to present our experiences of ECMO in patients with respiratory failure secondary to COVID-19.Methods:Data of 22 consecutive COVID-19 patients with severe respiratory failure whom were supported with ECMO were collected from computer-based hospital software retrospectively. Patients were treated in a single medical center between April 23, 2020 and February 14, 2021. Patients were analyzed from the points of laboratory and inflammatory markers, ventilation and ECMO features.Results:The ages of patients were between 30 and 69 years (mean age: 56.3±10.63). All patients were under maximum ventilator support, with the prone position. All patients had elevated levels of inflammatory indicators as D-dimer and ferritin. The mean level of ferritin was 1,564±1,611 ng/mL. D-dimer value was maximum 10.000 mg/mL (mean: 5,215±3,104), CRP increased to 177 mg/L (mean: 159±71). Percent of lymphocytes decreased as low as 2% (mean: 4.16±2.10). The mean duration of veno-arterial (VA) ECMO was 1.6±0.94 days whereas, for veno-venous (VV) ECMO, it was 10.05±5 days. VA ECMO was decided due to cardiovascular collapse. Four patients with VA ECMO survived a maximum of 3 days. Four of (22.22%) of 18 VV ECMO supported patient’s blood gas values were at normal ranges, 3 of them needed tracheostomy, and all of could be discharged from the hospital.Conclusion:Although, ECMO support for severe respiratory failure patients with COVID-19 is more challenging than regular ECMO applications, especially VV ECMO usage should be reminded as a remedy. |
| first_indexed | 2024-04-10T13:00:42Z |
| format | Article |
| id | doaj.art-93e83dab6114486fb0023c41419e9b82 |
| institution | Directory Open Access Journal |
| issn | 2147-2688 2147-2688 |
| language | English |
| last_indexed | 2024-04-10T13:00:42Z |
| publishDate | 2021-06-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Haseki Tıp Bülteni |
| spelling | doaj.art-93e83dab6114486fb0023c41419e9b822023-02-15T16:13:10ZengGalenos YayineviHaseki Tıp Bülteni2147-26882147-26882021-06-01591253010.4274/haseki.galenos.2021.714413049054A Single Tertiary Center Outcomes on Cannulation Strategies and Extracorporeal Membrane Oxygenation in the Treatment of Respiratory Failure During COVID- 19 InfectionMustafa Ozer Ulukan0Atalay Karakaya1Yahya Yildiz2Didem Melis Oztas3Nurdan Kamilcelebi4Servet Ozdemir5Murat Ugurlucan6Korhan Erkanlı7 Istanbul Medipol University Faculty of Medicine, Department of Cardiovascular Surgery, Istanbul, Turkey Istanbul Medipol University Faculty of Medicine, Department of Cardiovascular Surgery, Istanbul, Turkey Istanbul Medipol University Faculty of Medicine, Department of Anesthesiology and Reanimation, Istanbul, Turkey University of Health Sciences Turkey, Bagcılar Training and Research Hospital, Clinic of Cardiovascular Surgery, Istanbul, Turkey Istanbul Medipol University Faculty of Medicine, Department of Anesthesiology and Reanimation, Istanbul, Turkey Bakırköy Training and Research Hospital, Clinic of Thoracic Surgery, Istanbul, Turkey Istanbul Medipol University Faculty of Medicine, Department of Cardiovascular Surgery, Istanbul, Turkey Istanbul Medipol University Faculty of Medicine, Department of Cardiovascular Surgery, Istanbul, Turkey Aim:Extracorporeal membrane oxygenation (ECMO) is an important option for the management of severe acute respiratory distress syndrome (ARDS) in Coronavirus disease-2019 (COVID-19) cases. We aimed to present our experiences of ECMO in patients with respiratory failure secondary to COVID-19.Methods:Data of 22 consecutive COVID-19 patients with severe respiratory failure whom were supported with ECMO were collected from computer-based hospital software retrospectively. Patients were treated in a single medical center between April 23, 2020 and February 14, 2021. Patients were analyzed from the points of laboratory and inflammatory markers, ventilation and ECMO features.Results:The ages of patients were between 30 and 69 years (mean age: 56.3±10.63). All patients were under maximum ventilator support, with the prone position. All patients had elevated levels of inflammatory indicators as D-dimer and ferritin. The mean level of ferritin was 1,564±1,611 ng/mL. D-dimer value was maximum 10.000 mg/mL (mean: 5,215±3,104), CRP increased to 177 mg/L (mean: 159±71). Percent of lymphocytes decreased as low as 2% (mean: 4.16±2.10). The mean duration of veno-arterial (VA) ECMO was 1.6±0.94 days whereas, for veno-venous (VV) ECMO, it was 10.05±5 days. VA ECMO was decided due to cardiovascular collapse. Four patients with VA ECMO survived a maximum of 3 days. Four of (22.22%) of 18 VV ECMO supported patient’s blood gas values were at normal ranges, 3 of them needed tracheostomy, and all of could be discharged from the hospital.Conclusion:Although, ECMO support for severe respiratory failure patients with COVID-19 is more challenging than regular ECMO applications, especially VV ECMO usage should be reminded as a remedy. http://www.hasekidergisi.com/archives/archive-detail/article-preview/a-single-tertiary-center-outcomes-on-cannulation-s/48061 covid-19extracorporeal membrane oxygenationmulti-organ failure |
| spellingShingle | Mustafa Ozer Ulukan Atalay Karakaya Yahya Yildiz Didem Melis Oztas Nurdan Kamilcelebi Servet Ozdemir Murat Ugurlucan Korhan Erkanlı A Single Tertiary Center Outcomes on Cannulation Strategies and Extracorporeal Membrane Oxygenation in the Treatment of Respiratory Failure During COVID- 19 Infection Haseki Tıp Bülteni covid-19 extracorporeal membrane oxygenation multi-organ failure |
| title | A Single Tertiary Center Outcomes on Cannulation Strategies and Extracorporeal Membrane Oxygenation in the Treatment of Respiratory Failure During COVID- 19 Infection |
| title_full | A Single Tertiary Center Outcomes on Cannulation Strategies and Extracorporeal Membrane Oxygenation in the Treatment of Respiratory Failure During COVID- 19 Infection |
| title_fullStr | A Single Tertiary Center Outcomes on Cannulation Strategies and Extracorporeal Membrane Oxygenation in the Treatment of Respiratory Failure During COVID- 19 Infection |
| title_full_unstemmed | A Single Tertiary Center Outcomes on Cannulation Strategies and Extracorporeal Membrane Oxygenation in the Treatment of Respiratory Failure During COVID- 19 Infection |
| title_short | A Single Tertiary Center Outcomes on Cannulation Strategies and Extracorporeal Membrane Oxygenation in the Treatment of Respiratory Failure During COVID- 19 Infection |
| title_sort | single tertiary center outcomes on cannulation strategies and extracorporeal membrane oxygenation in the treatment of respiratory failure during covid 19 infection |
| topic | covid-19 extracorporeal membrane oxygenation multi-organ failure |
| url |
http://www.hasekidergisi.com/archives/archive-detail/article-preview/a-single-tertiary-center-outcomes-on-cannulation-s/48061
|
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