Rhodoquinone biosynthesis in C. elegans requires precursors generated by the kynurenine pathway
Parasitic helminths infect over a billion humans. To survive in the low oxygen environment of their hosts, these parasites use unusual anaerobic metabolism — this requires rhodoquinone (RQ), an electron carrier that is made by very few animal species. Crucially RQ is not made or used by any parasiti...
Main Authors: | Samantha Del Borrello, Margot Lautens, Kathleen Dolan, June H Tan, Taylor Davie, Michael R Schertzberg, Mark A Spensley, Amy A Caudy, Andrew G Fraser |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/48165 |
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