Association between presence of 20 or more natural teeth and all-cause, cancer-related, and cardiovascular disease-related mortality: Yamagata (Takahata) prospective observational study
Abstract Background Several studies have surveyed the relationship between the presence of ≥ 20 natural teeth and mortality. However, very few have evaluated this association over a long-term follow-up of more than ten years within a large population in Japan. This study aimed to prospectively confi...
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| Format: | Article |
| Language: | English |
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BMC
2020-12-01
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| Series: | BMC Oral Health |
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| Online Access: | https://doi.org/10.1186/s12903-020-01346-6 |
| _version_ | 1818384824774164480 |
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| author | Shigeo Ishikawa Tsuneo Konta Shinji Susa Kenichi Ishizawa Hitoshi Togashi Yoshiyuki Ueno Hidetoshi Yamashita Takamasa Kayama Mitsuyoshi Iino |
| author_facet | Shigeo Ishikawa Tsuneo Konta Shinji Susa Kenichi Ishizawa Hitoshi Togashi Yoshiyuki Ueno Hidetoshi Yamashita Takamasa Kayama Mitsuyoshi Iino |
| author_sort | Shigeo Ishikawa |
| collection | DOAJ |
| description | Abstract Background Several studies have surveyed the relationship between the presence of ≥ 20 natural teeth and mortality. However, very few have evaluated this association over a long-term follow-up of more than ten years within a large population in Japan. This study aimed to prospectively confirm the associations between mortality and the presence of ≥ 20 natural teeth within a community-based population in Japan. Methods A prospective observational study including 2208 participants aged ≥ 40 years was conducted in Takahata Town, Japan, between May 2005 and December 2016. All participants answered a self-administered questionnaire to provide their background characteristics, including their number of teeth. The participants were classified into two categories based on their self-reported number of teeth (< 20 and ≥ 20 teeth). Hazard ratios (HR) and 95% confidence intervals (CI) were calculated using Cox proportional-hazards regression model to assess risk factors for all-cause, cancer-, and cardiovascular disease-related mortality. Results The total follow-up period was 131.4 ± 24.1 months (mean ± SD). After adjusting for covariates, the risk of all-cause mortality was significantly higher in the group with < 20 teeth than in those with ≥ 20 teeth (HR = 1.604, 95% CI 1.007–2.555, p = 0.047). However, the risk of cancer- and cardiovascular disease-related mortalities was not statistically significant between the two groups. Conclusion In this study, participants with < 20 teeth had a significantly higher risk of all-cause mortality, although the difference was borderline significant. These results emphasize the importance of having ≥ 20 natural teeth for a healthy life expectancy. |
| first_indexed | 2024-12-14T03:28:24Z |
| format | Article |
| id | doaj.art-93edb88cd0654b688ba2f5a81d341686 |
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| issn | 1472-6831 |
| language | English |
| last_indexed | 2024-12-14T03:28:24Z |
| publishDate | 2020-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj.art-93edb88cd0654b688ba2f5a81d3416862022-12-21T23:18:50ZengBMCBMC Oral Health1472-68312020-12-0120111210.1186/s12903-020-01346-6Association between presence of 20 or more natural teeth and all-cause, cancer-related, and cardiovascular disease-related mortality: Yamagata (Takahata) prospective observational studyShigeo Ishikawa0Tsuneo Konta1Shinji Susa2Kenichi Ishizawa3Hitoshi Togashi4Yoshiyuki Ueno5Hidetoshi Yamashita6Takamasa Kayama7Mitsuyoshi Iino8Department of Dentistry, Oral and Maxillofacial Plastic and Reconstructive Surgery, Faculty of Medicine, Yamagata UniversityDepartment of Public Health and Hygiene, Yamagata University Graduate School of MedicineDepartment of Neurology, Hematology, Metabolism, Endocrinology and Diabetology, Yamagata University Faculty of MedicineDepartment of Neurology, Hematology, Metabolism, Endocrinology and Diabetology, Yamagata University Faculty of MedicineYamagata University Health Administration CentreGlobal Center of Excellence, Yamagata University School of MedicineGlobal Center of Excellence, Yamagata University School of MedicineGlobal Center of Excellence, Yamagata University School of MedicineDepartment of Dentistry, Oral and Maxillofacial Plastic and Reconstructive Surgery, Faculty of Medicine, Yamagata UniversityAbstract Background Several studies have surveyed the relationship between the presence of ≥ 20 natural teeth and mortality. However, very few have evaluated this association over a long-term follow-up of more than ten years within a large population in Japan. This study aimed to prospectively confirm the associations between mortality and the presence of ≥ 20 natural teeth within a community-based population in Japan. Methods A prospective observational study including 2208 participants aged ≥ 40 years was conducted in Takahata Town, Japan, between May 2005 and December 2016. All participants answered a self-administered questionnaire to provide their background characteristics, including their number of teeth. The participants were classified into two categories based on their self-reported number of teeth (< 20 and ≥ 20 teeth). Hazard ratios (HR) and 95% confidence intervals (CI) were calculated using Cox proportional-hazards regression model to assess risk factors for all-cause, cancer-, and cardiovascular disease-related mortality. Results The total follow-up period was 131.4 ± 24.1 months (mean ± SD). After adjusting for covariates, the risk of all-cause mortality was significantly higher in the group with < 20 teeth than in those with ≥ 20 teeth (HR = 1.604, 95% CI 1.007–2.555, p = 0.047). However, the risk of cancer- and cardiovascular disease-related mortalities was not statistically significant between the two groups. Conclusion In this study, participants with < 20 teeth had a significantly higher risk of all-cause mortality, although the difference was borderline significant. These results emphasize the importance of having ≥ 20 natural teeth for a healthy life expectancy.https://doi.org/10.1186/s12903-020-01346-6Tooth lossMortalityProspective studyObservational studyProportional-hazards model |
| spellingShingle | Shigeo Ishikawa Tsuneo Konta Shinji Susa Kenichi Ishizawa Hitoshi Togashi Yoshiyuki Ueno Hidetoshi Yamashita Takamasa Kayama Mitsuyoshi Iino Association between presence of 20 or more natural teeth and all-cause, cancer-related, and cardiovascular disease-related mortality: Yamagata (Takahata) prospective observational study BMC Oral Health Tooth loss Mortality Prospective study Observational study Proportional-hazards model |
| title | Association between presence of 20 or more natural teeth and all-cause, cancer-related, and cardiovascular disease-related mortality: Yamagata (Takahata) prospective observational study |
| title_full | Association between presence of 20 or more natural teeth and all-cause, cancer-related, and cardiovascular disease-related mortality: Yamagata (Takahata) prospective observational study |
| title_fullStr | Association between presence of 20 or more natural teeth and all-cause, cancer-related, and cardiovascular disease-related mortality: Yamagata (Takahata) prospective observational study |
| title_full_unstemmed | Association between presence of 20 or more natural teeth and all-cause, cancer-related, and cardiovascular disease-related mortality: Yamagata (Takahata) prospective observational study |
| title_short | Association between presence of 20 or more natural teeth and all-cause, cancer-related, and cardiovascular disease-related mortality: Yamagata (Takahata) prospective observational study |
| title_sort | association between presence of 20 or more natural teeth and all cause cancer related and cardiovascular disease related mortality yamagata takahata prospective observational study |
| topic | Tooth loss Mortality Prospective study Observational study Proportional-hazards model |
| url | https://doi.org/10.1186/s12903-020-01346-6 |
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