Recent Advances in the Use of Surface-Enhanced Raman Scattering for Illicit Drug Detection
The rapid increase in illicit drug use and its adverse health effects and socio-economic consequences have reached alarming proportions in recent years. Surface-enhanced Raman scattering (SERS) has emerged as a highly sensitive analytical tool for the detection of low dosages of drugs in liquid and...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-05-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/22/10/3877 |
| _version_ | 1797495613562028032 |
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| author | Shamim Azimi Aristides Docoslis |
| author_facet | Shamim Azimi Aristides Docoslis |
| author_sort | Shamim Azimi |
| collection | DOAJ |
| description | The rapid increase in illicit drug use and its adverse health effects and socio-economic consequences have reached alarming proportions in recent years. Surface-enhanced Raman scattering (SERS) has emerged as a highly sensitive analytical tool for the detection of low dosages of drugs in liquid and solid samples. In the present article, we review the state-of-the-art use of SERS for chemical analysis of illicit drugs in aqueous and complex biological samples, including saliva, urine, and blood. We also include a review of the types of SERS substrates used for this purpose, pointing out recent advancements in substrate fabrication towards quantitative and qualitative detection of illicit drugs. Finally, we conclude by providing our perspective on the field of SERS-based drug detection, including presently faced challenges. Overall, our review provides evidence of the strong potential of SERS to establish itself as both a laboratory and in situ analytical method for fast and sensitive drug detection and identification. |
| first_indexed | 2024-03-10T01:53:06Z |
| format | Article |
| id | doaj.art-93ee7ecafa2d4800a3a7f74eeca8464c |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T01:53:06Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-93ee7ecafa2d4800a3a7f74eeca8464c2023-11-23T13:02:48ZengMDPI AGSensors1424-82202022-05-012210387710.3390/s22103877Recent Advances in the Use of Surface-Enhanced Raman Scattering for Illicit Drug DetectionShamim Azimi0Aristides Docoslis1Department of Chemical Engineering, Queen’s University, Kingston, ON K7L 3N6, CanadaDepartment of Chemical Engineering, Queen’s University, Kingston, ON K7L 3N6, CanadaThe rapid increase in illicit drug use and its adverse health effects and socio-economic consequences have reached alarming proportions in recent years. Surface-enhanced Raman scattering (SERS) has emerged as a highly sensitive analytical tool for the detection of low dosages of drugs in liquid and solid samples. In the present article, we review the state-of-the-art use of SERS for chemical analysis of illicit drugs in aqueous and complex biological samples, including saliva, urine, and blood. We also include a review of the types of SERS substrates used for this purpose, pointing out recent advancements in substrate fabrication towards quantitative and qualitative detection of illicit drugs. Finally, we conclude by providing our perspective on the field of SERS-based drug detection, including presently faced challenges. Overall, our review provides evidence of the strong potential of SERS to establish itself as both a laboratory and in situ analytical method for fast and sensitive drug detection and identification.https://www.mdpi.com/1424-8220/22/10/3877surface-enhanced Raman scatteringRaman spectroscopypoint-of-care diagnosticsdrug detectionillicit drugs |
| spellingShingle | Shamim Azimi Aristides Docoslis Recent Advances in the Use of Surface-Enhanced Raman Scattering for Illicit Drug Detection Sensors surface-enhanced Raman scattering Raman spectroscopy point-of-care diagnostics drug detection illicit drugs |
| title | Recent Advances in the Use of Surface-Enhanced Raman Scattering for Illicit Drug Detection |
| title_full | Recent Advances in the Use of Surface-Enhanced Raman Scattering for Illicit Drug Detection |
| title_fullStr | Recent Advances in the Use of Surface-Enhanced Raman Scattering for Illicit Drug Detection |
| title_full_unstemmed | Recent Advances in the Use of Surface-Enhanced Raman Scattering for Illicit Drug Detection |
| title_short | Recent Advances in the Use of Surface-Enhanced Raman Scattering for Illicit Drug Detection |
| title_sort | recent advances in the use of surface enhanced raman scattering for illicit drug detection |
| topic | surface-enhanced Raman scattering Raman spectroscopy point-of-care diagnostics drug detection illicit drugs |
| url | https://www.mdpi.com/1424-8220/22/10/3877 |
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