Targeting Carbonic Anhydrase IX Activity and Expression
Metastatic tumors are often hypoxic exhibiting a decrease in extracellular pH (~6.5) due to a metabolic transition described by the Warburg Effect. This shift in tumor cell metabolism alters the tumor milieu inducing tumor cell proliferation, angiogenesis, cell motility, invasiveness, and often res...
主要な著者: | , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
MDPI AG
2015-01-01
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シリーズ: | Molecules |
主題: | |
オンライン・アクセス: | http://www.mdpi.com/1420-3049/20/2/2323 |