A Sensitive Voltammetric Approach Employing a Bare Boron-Doped Diamond Electrode as a Sensor for the Determination of Hydroxocobalamin
The voltammetric behavior of hydroxocobalamin (OH-CBL) was firstly studied by employing a bare boron-doped diamond electrode as a working electrode. It was found that OH-CBL provided four anodic signals on BDDE in acidic supporting electrolytes and one cathodic signal. The anodic peak situated at +4...
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MDPI AG
2023-09-01
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| Series: | Engineering Proceedings |
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| Online Access: | https://www.mdpi.com/2673-4591/48/1/7 |
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| author | Lenka Janíková Renáta Šelešovská Iveta Stýblová Jaromíra Chýlková |
| author_facet | Lenka Janíková Renáta Šelešovská Iveta Stýblová Jaromíra Chýlková |
| author_sort | Lenka Janíková |
| collection | DOAJ |
| description | The voltammetric behavior of hydroxocobalamin (OH-CBL) was firstly studied by employing a bare boron-doped diamond electrode as a working electrode. It was found that OH-CBL provided four anodic signals on BDDE in acidic supporting electrolytes and one cathodic signal. The anodic peak situated at +412 mV (<i>vs.</i> Ag|AgCl|KCl (sat.) recorded in 0.1 mol/L H<sub>2</sub>SO<sub>4</sub>) was found to be suitable for analytical purposes due to its position and shape. A novel voltammetric approach based on differential pulse voltammetry was developed and it was found as a sensitive analytical tool, with low limit of detection (LD = 13.2 nmol/L), applicable in analysis of vitamin preparations. |
| first_indexed | 2024-04-24T18:20:26Z |
| format | Article |
| id | doaj.art-93f4bfd9d82246f3b63220c96377d448 |
| institution | Directory Open Access Journal |
| issn | 2673-4591 |
| language | English |
| last_indexed | 2024-04-24T18:20:26Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Engineering Proceedings |
| spelling | doaj.art-93f4bfd9d82246f3b63220c96377d4482024-03-27T13:36:02ZengMDPI AGEngineering Proceedings2673-45912023-09-01481710.3390/CSAC2023-14894A Sensitive Voltammetric Approach Employing a Bare Boron-Doped Diamond Electrode as a Sensor for the Determination of HydroxocobalaminLenka Janíková0Renáta Šelešovská1Iveta Stýblová2Jaromíra Chýlková3Institute of Environmental and Chemical Engineering, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech RepublicInstitute of Environmental and Chemical Engineering, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech RepublicInstitute of Environmental and Chemical Engineering, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech RepublicInstitute of Environmental and Chemical Engineering, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech RepublicThe voltammetric behavior of hydroxocobalamin (OH-CBL) was firstly studied by employing a bare boron-doped diamond electrode as a working electrode. It was found that OH-CBL provided four anodic signals on BDDE in acidic supporting electrolytes and one cathodic signal. The anodic peak situated at +412 mV (<i>vs.</i> Ag|AgCl|KCl (sat.) recorded in 0.1 mol/L H<sub>2</sub>SO<sub>4</sub>) was found to be suitable for analytical purposes due to its position and shape. A novel voltammetric approach based on differential pulse voltammetry was developed and it was found as a sensitive analytical tool, with low limit of detection (LD = 13.2 nmol/L), applicable in analysis of vitamin preparations.https://www.mdpi.com/2673-4591/48/1/7hydroxocobalaminvitamin B12boron-doped diamond electrodevoltammetryvitamin analysis |
| spellingShingle | Lenka Janíková Renáta Šelešovská Iveta Stýblová Jaromíra Chýlková A Sensitive Voltammetric Approach Employing a Bare Boron-Doped Diamond Electrode as a Sensor for the Determination of Hydroxocobalamin Engineering Proceedings hydroxocobalamin vitamin B12 boron-doped diamond electrode voltammetry vitamin analysis |
| title | A Sensitive Voltammetric Approach Employing a Bare Boron-Doped Diamond Electrode as a Sensor for the Determination of Hydroxocobalamin |
| title_full | A Sensitive Voltammetric Approach Employing a Bare Boron-Doped Diamond Electrode as a Sensor for the Determination of Hydroxocobalamin |
| title_fullStr | A Sensitive Voltammetric Approach Employing a Bare Boron-Doped Diamond Electrode as a Sensor for the Determination of Hydroxocobalamin |
| title_full_unstemmed | A Sensitive Voltammetric Approach Employing a Bare Boron-Doped Diamond Electrode as a Sensor for the Determination of Hydroxocobalamin |
| title_short | A Sensitive Voltammetric Approach Employing a Bare Boron-Doped Diamond Electrode as a Sensor for the Determination of Hydroxocobalamin |
| title_sort | sensitive voltammetric approach employing a bare boron doped diamond electrode as a sensor for the determination of hydroxocobalamin |
| topic | hydroxocobalamin vitamin B12 boron-doped diamond electrode voltammetry vitamin analysis |
| url | https://www.mdpi.com/2673-4591/48/1/7 |
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