Di-(2-ethylhexyl)phthalate and Pyranon Derivated from Endophytic fungi <i>Penicillium</i> sp the Leave of Kunyit Putih (<i>Curcuma zedoaria</i>)

Two compounds from cultivation of the endophytic fungi Penicillium sp of leaves of kunyit putih (Curcuma zedoaria have been isolated. The endophytic fungus was cultivated on 5 L of Potatos Dextrose Broth (PDB) medium at room temperature (no shaking) for 3 weeks. The cultures were extracted with ethy...

Full description

Bibliographic Details
Main Authors: Muharni Muharni, Fitrya Fitrya, Milanti Okta Ruliza, Dwi Anjar Susanti, Elfita Elfita
Format: Article
Language:English
Published: Department of Chemistry, Universitas Gadjah Mada 2014-10-01
Series:Indonesian Journal of Chemistry
Subjects:
Online Access:https://jurnal.ugm.ac.id/ijc/article/view/21241
_version_ 1819118615225434112
author Muharni Muharni
Fitrya Fitrya
Milanti Okta Ruliza
Dwi Anjar Susanti
Elfita Elfita
author_facet Muharni Muharni
Fitrya Fitrya
Milanti Okta Ruliza
Dwi Anjar Susanti
Elfita Elfita
author_sort Muharni Muharni
collection DOAJ
description Two compounds from cultivation of the endophytic fungi Penicillium sp of leaves of kunyit putih (Curcuma zedoaria have been isolated. The endophytic fungus was cultivated on 5 L of Potatos Dextrose Broth (PDB) medium at room temperature (no shaking) for 3 weeks. The cultures were extracted with ethyl acetate to afford 3.0 g of residue after removal of the solvent under reduced pressure. The extract was separated and purified by silica gel column chromatography (CC) and afforded two pure compounds as colorless oily liquid (compound 1) and yellow crystal (compound 2). The structure of these compounds were characterized by detailed UV, IR, and NMR spectroscopic analysis and compound 1 as well as comparison with the reported data. Base on spectra analysis the compound 1 was determined as Di-(2-ethylhexyl)phthalate and compound 2 as 5-(4’-ethoxy-2’-hydroxy-5’-methyl-2’,3’-dihydrofuran-3’-il (hydroxy) methyl-4-isopropyl-3-methyl-2-pyran-2-on). Compound 1 is not new compound, but it is new for endophytic fungus from C. zeodoria and compound 2 is new compound.
first_indexed 2024-12-22T05:51:41Z
format Article
id doaj.art-93f5996f8b544bc3848762612b5827d9
institution Directory Open Access Journal
issn 1411-9420
2460-1578
language English
last_indexed 2024-12-22T05:51:41Z
publishDate 2014-10-01
publisher Department of Chemistry, Universitas Gadjah Mada
record_format Article
series Indonesian Journal of Chemistry
spelling doaj.art-93f5996f8b544bc3848762612b5827d92022-12-21T18:36:50ZengDepartment of Chemistry, Universitas Gadjah MadaIndonesian Journal of Chemistry1411-94202460-15782014-10-0114329029610.22146/ijc.2124114339Di-(2-ethylhexyl)phthalate and Pyranon Derivated from Endophytic fungi <i>Penicillium</i> sp the Leave of Kunyit Putih (<i>Curcuma zedoaria</i>)Muharni Muharni0Fitrya Fitrya1Milanti Okta Ruliza2Dwi Anjar Susanti3Elfita Elfita4Department of Chemistry, Faculty of Mathematics and Natural Sciences , Sriwijaya University, Jl. Raya Palembang Prabumulih Km 32, Indralaya, Ogan Ilir, South Sumatera 30662Department of Pharmacy, Faculty of Mathematics and Natural Sciences , Sriwijaya University, Jl. Raya Palembang Prabumulih Km 32, Indralaya, Ogan Ilir, South Sumatera 30662Department of Chemistry, Faculty of Mathematics and Natural Sciences , Sriwijaya University, Jl. Raya Palembang Prabumulih Km 32, Indralaya, Ogan Ilir, South Sumatera 30662Department of Chemistry, Faculty of Mathematics and Natural Sciences , Sriwijaya University, Jl. Raya Palembang Prabumulih Km 32, Indralaya, Ogan Ilir, South Sumatera 30662Department of Chemistry, Faculty of Mathematics and Natural Sciences , Sriwijaya University, Jl. Raya Palembang Prabumulih Km 32, Indralaya, Ogan Ilir, South Sumatera 30662Two compounds from cultivation of the endophytic fungi Penicillium sp of leaves of kunyit putih (Curcuma zedoaria have been isolated. The endophytic fungus was cultivated on 5 L of Potatos Dextrose Broth (PDB) medium at room temperature (no shaking) for 3 weeks. The cultures were extracted with ethyl acetate to afford 3.0 g of residue after removal of the solvent under reduced pressure. The extract was separated and purified by silica gel column chromatography (CC) and afforded two pure compounds as colorless oily liquid (compound 1) and yellow crystal (compound 2). The structure of these compounds were characterized by detailed UV, IR, and NMR spectroscopic analysis and compound 1 as well as comparison with the reported data. Base on spectra analysis the compound 1 was determined as Di-(2-ethylhexyl)phthalate and compound 2 as 5-(4’-ethoxy-2’-hydroxy-5’-methyl-2’,3’-dihydrofuran-3’-il (hydroxy) methyl-4-isopropyl-3-methyl-2-pyran-2-on). Compound 1 is not new compound, but it is new for endophytic fungus from C. zeodoria and compound 2 is new compound.https://jurnal.ugm.ac.id/ijc/article/view/21241endophytic fungiPenicillium spCurcuma zedoaria
spellingShingle Muharni Muharni
Fitrya Fitrya
Milanti Okta Ruliza
Dwi Anjar Susanti
Elfita Elfita
Di-(2-ethylhexyl)phthalate and Pyranon Derivated from Endophytic fungi <i>Penicillium</i> sp the Leave of Kunyit Putih (<i>Curcuma zedoaria</i>)
Indonesian Journal of Chemistry
endophytic fungi
Penicillium sp
Curcuma zedoaria
title Di-(2-ethylhexyl)phthalate and Pyranon Derivated from Endophytic fungi <i>Penicillium</i> sp the Leave of Kunyit Putih (<i>Curcuma zedoaria</i>)
title_full Di-(2-ethylhexyl)phthalate and Pyranon Derivated from Endophytic fungi <i>Penicillium</i> sp the Leave of Kunyit Putih (<i>Curcuma zedoaria</i>)
title_fullStr Di-(2-ethylhexyl)phthalate and Pyranon Derivated from Endophytic fungi <i>Penicillium</i> sp the Leave of Kunyit Putih (<i>Curcuma zedoaria</i>)
title_full_unstemmed Di-(2-ethylhexyl)phthalate and Pyranon Derivated from Endophytic fungi <i>Penicillium</i> sp the Leave of Kunyit Putih (<i>Curcuma zedoaria</i>)
title_short Di-(2-ethylhexyl)phthalate and Pyranon Derivated from Endophytic fungi <i>Penicillium</i> sp the Leave of Kunyit Putih (<i>Curcuma zedoaria</i>)
title_sort di 2 ethylhexyl phthalate and pyranon derivated from endophytic fungi i penicillium i sp the leave of kunyit putih i curcuma zedoaria i
topic endophytic fungi
Penicillium sp
Curcuma zedoaria
url https://jurnal.ugm.ac.id/ijc/article/view/21241
work_keys_str_mv AT muharnimuharni di2ethylhexylphthalateandpyranonderivatedfromendophyticfungiipenicilliumisptheleaveofkunyitputihicurcumazedoariai
AT fitryafitrya di2ethylhexylphthalateandpyranonderivatedfromendophyticfungiipenicilliumisptheleaveofkunyitputihicurcumazedoariai
AT milantioktaruliza di2ethylhexylphthalateandpyranonderivatedfromendophyticfungiipenicilliumisptheleaveofkunyitputihicurcumazedoariai
AT dwianjarsusanti di2ethylhexylphthalateandpyranonderivatedfromendophyticfungiipenicilliumisptheleaveofkunyitputihicurcumazedoariai
AT elfitaelfita di2ethylhexylphthalateandpyranonderivatedfromendophyticfungiipenicilliumisptheleaveofkunyitputihicurcumazedoariai