Nongenetic surface engineering of mesenchymal stromal cells with polyvalent antibodies to enhance targeting efficiency
Abstract Systemic infusion is a prevalent administration method for mesenchymal stromal cells (MSCs) in clinical trials. However, the inability to deliver a large number of therapeutic cells to diseased tissue is a substantial barrier. Here, we demonstrate that surface engineering of MSCs with polyv...
Main Authors: | Tenghui Ye, Xi Liu, Xianghua Zhong, Ran Yan, Peng Shi |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-41609-8 |
Similar Items
-
Nongenetic engineering of subcellular targeted therapeutic agents to facilitate precise cell activity manipulation
by: Do, Cong Thang
Published: (2022) -
Nongenetic paternal effects via seminal fluid
by: Leigh W. Simmons, et al.
Published: (2019-08-01) -
Nongenetic inheritance and multigenerational plasticity in the nematode C. elegans
by: L Ryan Baugh, et al.
Published: (2020-08-01) -
Stressed target cancer cells drive nongenetic reprogramming of CAR T cells and solid tumor microenvironment
by: Yufeng Wang, et al.
Published: (2023-09-01) -
Effect of sex and nongenetic factors on birth weight of Sahiwal calves
by: M MANOJ, et al.
Published: (2014-08-01)