Urinary cell-free DNA is a versatile analyte for monitoring infections of the urinary tract

Urinary tract infections are one of the most common infections in humans. Here, the authors use urinary cell-free DNA (cfDNA) to comprehensively monitor host and pathogen dynamics in bacterial and viral urinary tract infections, and show that it is a versatile analyte for monitoring urinary tract in...

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Main Authors: Philip Burnham, Darshana Dadhania, Michael Heyang, Fanny Chen, Lars F. Westblade, Manikkam Suthanthiran, John Richard Lee, Iwijn De Vlaminck
Format: Article
Language:English
Published: Nature Portfolio 2018-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04745-0
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author Philip Burnham
Darshana Dadhania
Michael Heyang
Fanny Chen
Lars F. Westblade
Manikkam Suthanthiran
John Richard Lee
Iwijn De Vlaminck
author_facet Philip Burnham
Darshana Dadhania
Michael Heyang
Fanny Chen
Lars F. Westblade
Manikkam Suthanthiran
John Richard Lee
Iwijn De Vlaminck
author_sort Philip Burnham
collection DOAJ
description Urinary tract infections are one of the most common infections in humans. Here, the authors use urinary cell-free DNA (cfDNA) to comprehensively monitor host and pathogen dynamics in bacterial and viral urinary tract infections, and show that it is a versatile analyte for monitoring urinary tract infections.
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spelling doaj.art-93f790d041bf490ca434880a7721580a2022-12-21T18:33:21ZengNature PortfolioNature Communications2041-17232018-06-019111010.1038/s41467-018-04745-0Urinary cell-free DNA is a versatile analyte for monitoring infections of the urinary tractPhilip Burnham0Darshana Dadhania1Michael Heyang2Fanny Chen3Lars F. Westblade4Manikkam Suthanthiran5John Richard Lee6Iwijn De Vlaminck7Meinig School of Biomedical Engineering, Cornell UniversityDivision of Nephrology and Hypertension, Department of Medicine, Weill Cornell MedicineMeinig School of Biomedical Engineering, Cornell UniversityMeinig School of Biomedical Engineering, Cornell UniversityDepartment of Pathology and Laboratory Medicine, Weill Cornell MedicineDivision of Nephrology and Hypertension, Department of Medicine, Weill Cornell MedicineDivision of Nephrology and Hypertension, Department of Medicine, Weill Cornell MedicineMeinig School of Biomedical Engineering, Cornell UniversityUrinary tract infections are one of the most common infections in humans. Here, the authors use urinary cell-free DNA (cfDNA) to comprehensively monitor host and pathogen dynamics in bacterial and viral urinary tract infections, and show that it is a versatile analyte for monitoring urinary tract infections.https://doi.org/10.1038/s41467-018-04745-0
spellingShingle Philip Burnham
Darshana Dadhania
Michael Heyang
Fanny Chen
Lars F. Westblade
Manikkam Suthanthiran
John Richard Lee
Iwijn De Vlaminck
Urinary cell-free DNA is a versatile analyte for monitoring infections of the urinary tract
Nature Communications
title Urinary cell-free DNA is a versatile analyte for monitoring infections of the urinary tract
title_full Urinary cell-free DNA is a versatile analyte for monitoring infections of the urinary tract
title_fullStr Urinary cell-free DNA is a versatile analyte for monitoring infections of the urinary tract
title_full_unstemmed Urinary cell-free DNA is a versatile analyte for monitoring infections of the urinary tract
title_short Urinary cell-free DNA is a versatile analyte for monitoring infections of the urinary tract
title_sort urinary cell free dna is a versatile analyte for monitoring infections of the urinary tract
url https://doi.org/10.1038/s41467-018-04745-0
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