Bullous Pemphigoid Successfully Treated with Rituximab

Bullous pemphigoid is an autoimmune disease characterized by subepidermal blister formation. Can be self-limiting but when necessary treatment includes the use of corticosteroids, immunosuppressants, and biological agents. We present the case of a 37 year old patient with a severe and refractory pre...

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Bibliographic Details
Main Authors: Nuno Silva, Andreia Costa, Fernando Salvador, Elisa Serradeiro
Format: Article
Language:English
Published: Ordem dos Médicos 2017-03-01
Series:Acta Médica Portuguesa
Subjects:
Online Access:http://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812
Description
Summary:Bullous pemphigoid is an autoimmune disease characterized by subepidermal blister formation. Can be self-limiting but when necessary treatment includes the use of corticosteroids, immunosuppressants, and biological agents. We present the case of a 37 year old patient with a severe and refractory presentation of bullous pemphigoid. After about a month of treatment with various first line drugs and with no response, we chose to start rituximab and clear improvement of the lesions was observed. The authors aim to highlight the usefulness and effectiveness of this drug in this disease.
ISSN:0870-399X
1646-0758