Shotgun Immunoproteomic Approach for the Discovery of Linear B-Cell Epitopes in Biothreat Agents Francisella tularensis and Burkholderia pseudomallei

Shotgun Immunoproteomic Approach for the Discovery of Linear B-Cell Epitopes in Biothreat Agents Francisella tularensis and Burkholderia pseudomallei

Peptide-based subunit vaccines are coming to the forefront of current vaccine approaches, with safety and cost-effective production among their top advantages. Peptide vaccine formulations consist of multiple synthetic linear epitopes that together trigger desired immune responses that can result in...

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Bibliographic Details
Main Authors: Patrik D’haeseleer, Nicole M. Collette, Victoria Lao, Brent W. Segelke, Steven S. Branda, Magdalena Franco
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
Francisella
Burkholderia
immunoproteome
B-cell epitope
antigen
peptide vaccine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.716676/full

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