High-resolution melt curve analysis: An approach for variant detection in the TPO gene of congenital hypothyroid patients in Bangladesh.
TPO (Thyroid Peroxidase) is known to be one of the major genes involved in congenital hypothyroid patients with thyroid dyshormonogenesis. The present study aims to validate high-resolution melting (HRM) curve analysis as a substitute method for Sanger sequencing, focusing on the frequently observed...
Main Authors: | , , , , , , , , , , , , , , , , , , , |
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פורמט: | Article |
שפה: | English |
יצא לאור: |
Public Library of Science (PLoS)
2024-01-01
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סדרה: | PLoS ONE |
גישה מקוונת: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0293570&type=printable |