NR-SAFE: a randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson’s disease

NR-SAFE: a randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson’s disease

Abstract Nicotinamide adenine dinucleotide (NAD) replenishment therapy using nicotinamide riboside (NR) shows promise for Parkinson’s disease (PD) and other neurodegenerative disorders. However, the optimal dose of NR remains unknown, and doses exceeding 2000 mg daily have not been tested in humans....

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Bibliographic Details
Main Authors:	Haakon Berven, Simon Kverneng, Erika Sheard, Mona Søgnen, Solveig Amdahl Af Geijerstam, Kristoffer Haugarvoll, Geir-Olve Skeie, Christian Dölle, Charalampos Tzoulis
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-11-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-023-43514-6

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