LC-MS/TOF Characterization and Stability Study of Artesunate in Different Solvent Systems
Artemisinin (ART) is a sesquiterpene lactone and a popular malaria drug used in many parts of the world. Artesunate (ARTS) is a semi-synthetic derivative of ART with improved pharmacokinetic properties. However, the half-life of ARTS is less than an hour in vivo. The analysis of this drug in vitro i...
Main Authors: | Kogila Oke, Amos Mugweru |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-08-01
|
Series: | Separations |
Subjects: | |
Online Access: | https://www.mdpi.com/2297-8739/9/8/218 |
Similar Items
-
Artemisinin and Its Derivatives as Potential Anticancer Agents
by: Luan Wen, et al.
Published: (2024-08-01) -
Artemisinin anti-malarial drugs in China
by: Zongru Guo
Published: (2016-03-01) -
Artemisinin DNA Base Interaction Studies in Presence of Fe(II): LC/TOF MS Separation of Reaction Products
by: Kogila Oke, et al.
Published: (2021-09-01) -
Therapeutic potential of artemisinin and its derivatives in managing kidney diseases
by: Qi Jin, et al.
Published: (2023-02-01) -
A Simplified Liquid Chromatography-Mass Spectrometry Assay for Artesunate and Dihydroartemisinin, Its Metabolite, in Human Plasma
by: Victor Meléndez, et al.
Published: (2010-12-01)