PM2.5-induced ADRB2 hypermethylation contributed to cardiac dysfunction through cardiomyocytes apoptosis via PI3K/Akt pathway

PM2.5-induced ADRB2 hypermethylation contributed to cardiac dysfunction through cardiomyocytes apoptosis via PI3K/Akt pathway

Background: Long-term exposure to fine particulate matter (PM2.5) can causally contribute to progression of atherosclerosis, risk of ischemic heart disease and death, but the underlying mechanism is little known. Since DNA methylation impacts the process of heart disease, it might be useful in explo...

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Bibliographic Details
Main Authors: Xiaozhe Yang, Tong Zhao, Lin Feng, Yanfeng Shi, Jinjin Jiang, Shuang Liang, Baiyang Sun, Qing Xu, Junchao Duan, Zhiwei Sun
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Environment International
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412019304969

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