Chrono-biology, Chrono-pharmacology, and Chrono-nutrition
The circadian clock system in mammals drives many physiological processes including the daily rhythms of sleep–wake behavior, hormonal secretion, and metabolism. This system responds to daily environmental changes, such as the light–dark cycle, food intake, and drug administration. In this review, w...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-01-01
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| Series: | Journal of Pharmacological Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319301835 |
| _version_ | 1818299192570806272 |
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| author | Yu Tahara Shigenobu Shibata |
| author_facet | Yu Tahara Shigenobu Shibata |
| author_sort | Yu Tahara |
| collection | DOAJ |
| description | The circadian clock system in mammals drives many physiological processes including the daily rhythms of sleep–wake behavior, hormonal secretion, and metabolism. This system responds to daily environmental changes, such as the light–dark cycle, food intake, and drug administration. In this review, we focus on the central and peripheral circadian clock systems in response to drugs, food, and nutrition. We also discuss the adaptation and anticipation mechanisms of our body with regard to clock system regulation of various kinetic and dynamic pathways, including absorption, distribution, metabolism, and excretion of drugs and nutrients. “Chronopharmacology” and “chrono-nutrition” are likely to become important research fields in chronobiological studies. Keywords:: circadian rhythm, Period 2 gene, liver, obesity, metabolism |
| first_indexed | 2024-12-13T04:47:19Z |
| format | Article |
| id | doaj.art-9401423e1d4344008891ac1c1f195f3b |
| institution | Directory Open Access Journal |
| issn | 1347-8613 |
| language | English |
| last_indexed | 2024-12-13T04:47:19Z |
| publishDate | 2014-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Pharmacological Sciences |
| spelling | doaj.art-9401423e1d4344008891ac1c1f195f3b2022-12-21T23:59:07ZengElsevierJournal of Pharmacological Sciences1347-86132014-01-011243320335Chrono-biology, Chrono-pharmacology, and Chrono-nutritionYu Tahara0Shigenobu Shibata1Laboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Tokyo 162-8480, JapanLaboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Tokyo 162-8480, Japan; Corresponding author. shibatas@waseda.jpThe circadian clock system in mammals drives many physiological processes including the daily rhythms of sleep–wake behavior, hormonal secretion, and metabolism. This system responds to daily environmental changes, such as the light–dark cycle, food intake, and drug administration. In this review, we focus on the central and peripheral circadian clock systems in response to drugs, food, and nutrition. We also discuss the adaptation and anticipation mechanisms of our body with regard to clock system regulation of various kinetic and dynamic pathways, including absorption, distribution, metabolism, and excretion of drugs and nutrients. “Chronopharmacology” and “chrono-nutrition” are likely to become important research fields in chronobiological studies. Keywords:: circadian rhythm, Period 2 gene, liver, obesity, metabolismhttp://www.sciencedirect.com/science/article/pii/S1347861319301835 |
| spellingShingle | Yu Tahara Shigenobu Shibata Chrono-biology, Chrono-pharmacology, and Chrono-nutrition Journal of Pharmacological Sciences |
| title | Chrono-biology, Chrono-pharmacology, and Chrono-nutrition |
| title_full | Chrono-biology, Chrono-pharmacology, and Chrono-nutrition |
| title_fullStr | Chrono-biology, Chrono-pharmacology, and Chrono-nutrition |
| title_full_unstemmed | Chrono-biology, Chrono-pharmacology, and Chrono-nutrition |
| title_short | Chrono-biology, Chrono-pharmacology, and Chrono-nutrition |
| title_sort | chrono biology chrono pharmacology and chrono nutrition |
| url | http://www.sciencedirect.com/science/article/pii/S1347861319301835 |
| work_keys_str_mv | AT yutahara chronobiologychronopharmacologyandchrononutrition AT shigenobushibata chronobiologychronopharmacologyandchrononutrition |