Changes in the Prevalence of Coccidian Protozoa in Immunocompromised Patients Over the Last Decade
Introduction: Coccidian protozoal infection is one of the most important causes of diarrhea, which could prove to be fatal in immunosuppressed patients. The present study aimed to determine changes in the incidences and prevalence of coccidian protozoa in immunocompromised patients in two different...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | Turkish |
| Published: |
Galenos Yayinevi
2021-12-01
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| Series: | Mediterranean Journal of Infection, Microbes and Antimicrobials |
| Subjects: | |
| Online Access: | http://mjima.org/abstract.php?id=248 |
| _version_ | 1828031188474789888 |
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| author | Özlem ULUSAN BAĞCI Orçun ZORBOZAN Kardelen YETİŞMİŞ Sema AYDOĞDU Fatma Ömür ARDENİZ Ayşe Deniz GÖKENGİN Mehmet KANTAR Eren SOYALTIN Önder YAVAŞCAN Fehmi AKÇİÇEK Nevin TURGAY |
| author_facet | Özlem ULUSAN BAĞCI Orçun ZORBOZAN Kardelen YETİŞMİŞ Sema AYDOĞDU Fatma Ömür ARDENİZ Ayşe Deniz GÖKENGİN Mehmet KANTAR Eren SOYALTIN Önder YAVAŞCAN Fehmi AKÇİÇEK Nevin TURGAY |
| author_sort | Özlem ULUSAN BAĞCI |
| collection | DOAJ |
| description | Introduction: Coccidian protozoal infection is one of the most important causes of diarrhea, which could prove to be fatal in immunosuppressed patients. The present study aimed to determine changes in the incidences and prevalence of coccidian protozoa in immunocompromised patients in two different time frames, and thus draw attention toward these neglected microorganisms.
Materials and Methods: The present study involved retrospective analysis of 311 stool samples obtained from 311 immunocompromised patients, collected over two time frames (2009 and 2016-2019).
Results: The study included 40.5% female and 37.6% pediatric immunocompromised patients (aged 0-18 years). In 2009, the incidences of Cryptosporidium spp. were 51.4% and this decreased to 41.6% in 2016-2019. Cyclospora spp. incidences decreased from 24.6% in 2009 to 9.8% in 2016-2019. Coccidian infection in pediatric patients was found to decrease over the stipulated time, where Cryptosporidium spp. incidences decreased from 63.9% to 34.6% and Cyclospora spp. detection rate decreased from 30.6% to 4.9%. In adults, detection rate for Cryptosporidium spp. changed from 47% to 47.8%, while Cyclospora spp. incidences changed from 22.5% to 14.1%, over the period of 10 years.
Conclusion: The study demonstrated no significant changes in coccidian parasitic detection rates in immunocompromised adults over the period of 10 years, which remained high. However, a significant decrease in the detection rates of both Cryptosporidium and Cyclospora spp. was reported in pediatric patients over the years. A comparison with previously reported data revealed higher detection rates of coccidian parasite in immunocompromised patients as compared to the general patient population. These results also highlighted the importance of detailed patient information, especially clinical diagnosis and drug usage, to ensure application of appropriate diagnostic methods for laboratory evaluation of the stool samples obtained from immunocompromised patients. This will further aid in early diagnosis and management of such infections. |
| first_indexed | 2024-04-10T14:41:44Z |
| format | Article |
| id | doaj.art-9404c5d5cac64671b7e76230098c8c2e |
| institution | Directory Open Access Journal |
| issn | 2147-673X |
| language | Turkish |
| last_indexed | 2024-04-10T14:41:44Z |
| publishDate | 2021-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Mediterranean Journal of Infection, Microbes and Antimicrobials |
| spelling | doaj.art-9404c5d5cac64671b7e76230098c8c2e2023-02-15T16:08:08ZturGalenos YayineviMediterranean Journal of Infection, Microbes and Antimicrobials2147-673X2021-12-0110110.4274/mjima.galenos.2021.2020.30Changes in the Prevalence of Coccidian Protozoa in Immunocompromised Patients Over the Last DecadeÖzlem ULUSAN BAĞCI0https://orcid.org/0000-0002-9695-5703Orçun ZORBOZAN1https://orcid.org/0000-0002-9645-7085Kardelen YETİŞMİŞ2https://orcid.org/0000-0001-7111-5807Sema AYDOĞDU3https://orcid.org/0000-0002-1678-7552Fatma Ömür ARDENİZ4https://orcid.org/0000-0003-3804-2065Ayşe Deniz GÖKENGİN5https://orcid.org/0000-0003-0704-2302Mehmet KANTAR6https://orcid.org/0000-0002-1669-4321Eren SOYALTIN7https://orcid.org/0000-0001-9744-7439Önder YAVAŞCAN8https://orcid.org/0000-0002-3582-5075Fehmi AKÇİÇEK9https://orcid.org/0000-0003-2583-4709Nevin TURGAY10https://orcid.org/0000-0003-4517-3223Ege University Faculty of Medicine, Department of Parasitology, İzmir, TurkeyEge University Faculty of Medicine, Department of Parasitology, İzmir, TurkeyEge University Institute of Health Sciences, İzmir, TurkeyEge University Faculty of Medicine, Department of Pediatric Gastroenterology, İzmir, TurkeyEge University Faculty of Medicine, Department of Internal Medicine, İzmir, TurkeyEge University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, İzmir, TurkeyEge University Faculty of Medicine, Department of Pediatric Health and Diseases, İzmir, TurkeyUniversity of Health Sciences Turkey, Tepecik Training and Research Hospital, Clinic of Pediatric Nephrology, İzmir, TurkeyUniversity of Health Sciences Turkey, Tepecik Training and Research Hospital, Clinic of Pediatric Nephrology, İzmir, TurkeyEge University Faculty of Medicine, Department of Internal Medicine, İzmir, TurkeyEge University Faculty of Medicine, Department of Parasitology, İzmir, TurkeyIntroduction: Coccidian protozoal infection is one of the most important causes of diarrhea, which could prove to be fatal in immunosuppressed patients. The present study aimed to determine changes in the incidences and prevalence of coccidian protozoa in immunocompromised patients in two different time frames, and thus draw attention toward these neglected microorganisms. Materials and Methods: The present study involved retrospective analysis of 311 stool samples obtained from 311 immunocompromised patients, collected over two time frames (2009 and 2016-2019). Results: The study included 40.5% female and 37.6% pediatric immunocompromised patients (aged 0-18 years). In 2009, the incidences of Cryptosporidium spp. were 51.4% and this decreased to 41.6% in 2016-2019. Cyclospora spp. incidences decreased from 24.6% in 2009 to 9.8% in 2016-2019. Coccidian infection in pediatric patients was found to decrease over the stipulated time, where Cryptosporidium spp. incidences decreased from 63.9% to 34.6% and Cyclospora spp. detection rate decreased from 30.6% to 4.9%. In adults, detection rate for Cryptosporidium spp. changed from 47% to 47.8%, while Cyclospora spp. incidences changed from 22.5% to 14.1%, over the period of 10 years. Conclusion: The study demonstrated no significant changes in coccidian parasitic detection rates in immunocompromised adults over the period of 10 years, which remained high. However, a significant decrease in the detection rates of both Cryptosporidium and Cyclospora spp. was reported in pediatric patients over the years. A comparison with previously reported data revealed higher detection rates of coccidian parasite in immunocompromised patients as compared to the general patient population. These results also highlighted the importance of detailed patient information, especially clinical diagnosis and drug usage, to ensure application of appropriate diagnostic methods for laboratory evaluation of the stool samples obtained from immunocompromised patients. This will further aid in early diagnosis and management of such infections.http://mjima.org/abstract.php?id=248cryptosporidiumcyclosporacoccidianimmunocompromised pediatric patientsinfectious diarrhea |
| spellingShingle | Özlem ULUSAN BAĞCI Orçun ZORBOZAN Kardelen YETİŞMİŞ Sema AYDOĞDU Fatma Ömür ARDENİZ Ayşe Deniz GÖKENGİN Mehmet KANTAR Eren SOYALTIN Önder YAVAŞCAN Fehmi AKÇİÇEK Nevin TURGAY Changes in the Prevalence of Coccidian Protozoa in Immunocompromised Patients Over the Last Decade Mediterranean Journal of Infection, Microbes and Antimicrobials cryptosporidium cyclospora coccidian immunocompromised pediatric patients infectious diarrhea |
| title | Changes in the Prevalence of Coccidian Protozoa in Immunocompromised Patients Over the Last Decade |
| title_full | Changes in the Prevalence of Coccidian Protozoa in Immunocompromised Patients Over the Last Decade |
| title_fullStr | Changes in the Prevalence of Coccidian Protozoa in Immunocompromised Patients Over the Last Decade |
| title_full_unstemmed | Changes in the Prevalence of Coccidian Protozoa in Immunocompromised Patients Over the Last Decade |
| title_short | Changes in the Prevalence of Coccidian Protozoa in Immunocompromised Patients Over the Last Decade |
| title_sort | changes in the prevalence of coccidian protozoa in immunocompromised patients over the last decade |
| topic | cryptosporidium cyclospora coccidian immunocompromised pediatric patients infectious diarrhea |
| url | http://mjima.org/abstract.php?id=248 |
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