The Common Combination of Aortic Stenosis with Mitral Regurgitation: Diagnostic Insight and Therapeutic Implications in the Modern Era of Advanced Echocardiography and Percutaneous Intervention

The combination of aortic stenosis (AS) and mitral regurgitation (MR) is common in patients with degenerative valvular disease. It is characterized by having complex pathophysiology, leading to potential diagnostic pitfalls. Evidence is scarce in the literature to direct the diagnostic framework and...

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Main Authors: Francesca Mantovani, Andrea Barbieri, Alessandro Albini, Niccolò Bonini, Diego Fanti, Simone Fezzi, Martina Setti, Andrea Rossi, Flavio Ribichini, Giovanni Benfari
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/19/4364
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author Francesca Mantovani
Andrea Barbieri
Alessandro Albini
Niccolò Bonini
Diego Fanti
Simone Fezzi
Martina Setti
Andrea Rossi
Flavio Ribichini
Giovanni Benfari
author_facet Francesca Mantovani
Andrea Barbieri
Alessandro Albini
Niccolò Bonini
Diego Fanti
Simone Fezzi
Martina Setti
Andrea Rossi
Flavio Ribichini
Giovanni Benfari
author_sort Francesca Mantovani
collection DOAJ
description The combination of aortic stenosis (AS) and mitral regurgitation (MR) is common in patients with degenerative valvular disease. It is characterized by having complex pathophysiology, leading to potential diagnostic pitfalls. Evidence is scarce in the literature to direct the diagnostic framework and treatment of patients with this particular combination of multiple valvular diseases. In this complex scenario, the appropriate use of advanced echocardiography and multimodality imaging methods plays a central role. Transcatheter mitral valve replacement or repair and transcatheter aortic valve replacement widen the surgical options for valve diseases. Therefore, there is an increasing need to reconsider the function, timing, and mode intervention for patients with a combination of AS with MR towards more personalized treatment.
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spelling doaj.art-9409230045d045c2ba73b660504ac3002023-11-22T16:18:19ZengMDPI AGJournal of Clinical Medicine2077-03832021-09-011019436410.3390/jcm10194364The Common Combination of Aortic Stenosis with Mitral Regurgitation: Diagnostic Insight and Therapeutic Implications in the Modern Era of Advanced Echocardiography and Percutaneous InterventionFrancesca Mantovani0Andrea Barbieri1Alessandro Albini2Niccolò Bonini3Diego Fanti4Simone Fezzi5Martina Setti6Andrea Rossi7Flavio Ribichini8Giovanni Benfari9Division of Cardiology, Azienda USL–IRCCS di Reggio Emilia, 42122 Reggio Emilia, ItalyDivision of Cardiology, Department of Diagnostics, Clinical and Public Health Medicine, Policlinico University Hospital of Modena, University of Modena and Reggio Emilia, 41121 Modena, ItalyDivision of Cardiology, Department of Diagnostics, Clinical and Public Health Medicine, Policlinico University Hospital of Modena, University of Modena and Reggio Emilia, 41121 Modena, ItalyDivision of Cardiology, Department of Diagnostics, Clinical and Public Health Medicine, Policlinico University Hospital of Modena, University of Modena and Reggio Emilia, 41121 Modena, ItalySection of Cardiology, University of Verona, 37129 Verona, ItalySection of Cardiology, University of Verona, 37129 Verona, ItalySection of Cardiology, University of Verona, 37129 Verona, ItalySection of Cardiology, University of Verona, 37129 Verona, ItalySection of Cardiology, University of Verona, 37129 Verona, ItalySection of Cardiology, University of Verona, 37129 Verona, ItalyThe combination of aortic stenosis (AS) and mitral regurgitation (MR) is common in patients with degenerative valvular disease. It is characterized by having complex pathophysiology, leading to potential diagnostic pitfalls. Evidence is scarce in the literature to direct the diagnostic framework and treatment of patients with this particular combination of multiple valvular diseases. In this complex scenario, the appropriate use of advanced echocardiography and multimodality imaging methods plays a central role. Transcatheter mitral valve replacement or repair and transcatheter aortic valve replacement widen the surgical options for valve diseases. Therefore, there is an increasing need to reconsider the function, timing, and mode intervention for patients with a combination of AS with MR towards more personalized treatment.https://www.mdpi.com/2077-0383/10/19/4364aortic stenosismitral regurgitationcombined heart valve diseaseechocardiographydiagnosistreatment
spellingShingle Francesca Mantovani
Andrea Barbieri
Alessandro Albini
Niccolò Bonini
Diego Fanti
Simone Fezzi
Martina Setti
Andrea Rossi
Flavio Ribichini
Giovanni Benfari
The Common Combination of Aortic Stenosis with Mitral Regurgitation: Diagnostic Insight and Therapeutic Implications in the Modern Era of Advanced Echocardiography and Percutaneous Intervention
Journal of Clinical Medicine
aortic stenosis
mitral regurgitation
combined heart valve disease
echocardiography
diagnosis
treatment
title The Common Combination of Aortic Stenosis with Mitral Regurgitation: Diagnostic Insight and Therapeutic Implications in the Modern Era of Advanced Echocardiography and Percutaneous Intervention
title_full The Common Combination of Aortic Stenosis with Mitral Regurgitation: Diagnostic Insight and Therapeutic Implications in the Modern Era of Advanced Echocardiography and Percutaneous Intervention
title_fullStr The Common Combination of Aortic Stenosis with Mitral Regurgitation: Diagnostic Insight and Therapeutic Implications in the Modern Era of Advanced Echocardiography and Percutaneous Intervention
title_full_unstemmed The Common Combination of Aortic Stenosis with Mitral Regurgitation: Diagnostic Insight and Therapeutic Implications in the Modern Era of Advanced Echocardiography and Percutaneous Intervention
title_short The Common Combination of Aortic Stenosis with Mitral Regurgitation: Diagnostic Insight and Therapeutic Implications in the Modern Era of Advanced Echocardiography and Percutaneous Intervention
title_sort common combination of aortic stenosis with mitral regurgitation diagnostic insight and therapeutic implications in the modern era of advanced echocardiography and percutaneous intervention
topic aortic stenosis
mitral regurgitation
combined heart valve disease
echocardiography
diagnosis
treatment
url https://www.mdpi.com/2077-0383/10/19/4364
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