Foot-and-mouth disease virus non-structural protein 2B downregulates the RLR signaling pathway via degradation of RIG-I and MDA5

Foot-and-mouth disease virus non-structural protein 2B downregulates the RLR signaling pathway via degradation of RIG-I and MDA5

Foot-and-mouth disease virus (FMDV) is a single-stranded, positive-sense RNA virus containing at least 13 proteins. Many of these proteins show immune modulation capabilities. As a non-structural protein of the FMDV, 2B is involved in the rearrangement of the host cell membranes and the disruption o...

Full description

Bibliographic Details
Main Authors: Asela Weerawardhana, Md Bashir Uddin, Joo-Hyung Choi, Prabuddha Pathinayake, Sung Ho Shin, Kiramage Chathuranga, Jong-Hyeon Park, Jong-Soo Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
foot and mouth disease virus (FMDV)
2B
RIG-I
MDA5
RNF125
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1020262/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1020262/full

Similar Items