Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial
ABSTRACT Introduction: Titanium tetrafluoride (TiF4) is a fluoride compound that, when is applied over enamel, promotes a protection against demineralization through a titanium dioxide (TiO2) acid-resistant coat. Objectives: This study sought to verify the hypothesis that a single application of 4...
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| Format: | Article |
| Language: | English |
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Dental Press Editora
2023-04-01
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| Series: | Dental Press Journal of Orthodontics |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512023000100303&lng=en&tlng=en |
| _version_ | 1797852863845629952 |
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| author | Ana Beatriz CHEVITARESE Karla Lorene de França LEITE Paulo Bechara DUTRA Matheus Melo PITHON Lucianne Cople Maia FARIA Antônio Carlos de Oliveira RUELLAS |
| author_facet | Ana Beatriz CHEVITARESE Karla Lorene de França LEITE Paulo Bechara DUTRA Matheus Melo PITHON Lucianne Cople Maia FARIA Antônio Carlos de Oliveira RUELLAS |
| author_sort | Ana Beatriz CHEVITARESE |
| collection | DOAJ |
| description | ABSTRACT Introduction: Titanium tetrafluoride (TiF4) is a fluoride compound that, when is applied over enamel, promotes a protection against demineralization through a titanium dioxide (TiO2) acid-resistant coat. Objectives: This study sought to verify the hypothesis that a single application of 4% TiF4 increases the resistance of enamel to dental demineralization in orthodontic patients. Materials and Methods: This controlled clinical trial followed CONSORT guidelines and investigated the prevention of enamel demineralization, fluoride retention, and the presence of a Ti layer after TiF4 application on banded teeth exposed to clinical cariogenic biofilm. Forty premolars were divided into a control group (CG; n = 20) and a test group (TG; n = 20). Teeth from both groups received prophylaxis and orthodontic bands with a cariogenic locus. In the TG, all teeth additionally underwent aqueous 4% TiF4 solution application after prophylaxis before being banded. After one month, teeth from both groups were extracted and prepared to assess the microhardness, fluoride retention, and evaluation of the Ti coating over the enamel surface. All data were analyzed with a paired Student’s t-test (p<0.05). Results: Enamel microhardness and fluoride uptake were higher in TG than in CG, while the Ti layer could be seen over TG teeth that received TiF4 application. Conclusion: Under clinical circumstances, the 4% aqueous TiF4 solution was effective in preventing enamel mineral loss through increasing the enamel resistance to dental demineralization, enhancing its microhardness and fluoride uptake, and forming a Ti coat. |
| first_indexed | 2024-04-09T19:41:12Z |
| format | Article |
| id | doaj.art-9409e61fed334ef4969fdf9cea69f121 |
| institution | Directory Open Access Journal |
| issn | 2177-6709 |
| language | English |
| last_indexed | 2024-04-09T19:41:12Z |
| publishDate | 2023-04-01 |
| publisher | Dental Press Editora |
| record_format | Article |
| series | Dental Press Journal of Orthodontics |
| spelling | doaj.art-9409e61fed334ef4969fdf9cea69f1212023-04-04T07:34:03ZengDental Press EditoraDental Press Journal of Orthodontics2177-67092023-04-0128110.1590/2177-6709.28.1.e2321304.oarEffect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trialAna Beatriz CHEVITARESEhttps://orcid.org/0000-0003-2140-7179Karla Lorene de França LEITEhttps://orcid.org/0000-0002-0113-6810Paulo Bechara DUTRAMatheus Melo PITHONhttps://orcid.org/0000-0002-8418-4139Lucianne Cople Maia FARIAhttps://orcid.org/0000-0003-1026-9401Antônio Carlos de Oliveira RUELLAShttps://orcid.org/0000-0001-7973-9286ABSTRACT Introduction: Titanium tetrafluoride (TiF4) is a fluoride compound that, when is applied over enamel, promotes a protection against demineralization through a titanium dioxide (TiO2) acid-resistant coat. Objectives: This study sought to verify the hypothesis that a single application of 4% TiF4 increases the resistance of enamel to dental demineralization in orthodontic patients. Materials and Methods: This controlled clinical trial followed CONSORT guidelines and investigated the prevention of enamel demineralization, fluoride retention, and the presence of a Ti layer after TiF4 application on banded teeth exposed to clinical cariogenic biofilm. Forty premolars were divided into a control group (CG; n = 20) and a test group (TG; n = 20). Teeth from both groups received prophylaxis and orthodontic bands with a cariogenic locus. In the TG, all teeth additionally underwent aqueous 4% TiF4 solution application after prophylaxis before being banded. After one month, teeth from both groups were extracted and prepared to assess the microhardness, fluoride retention, and evaluation of the Ti coating over the enamel surface. All data were analyzed with a paired Student’s t-test (p<0.05). Results: Enamel microhardness and fluoride uptake were higher in TG than in CG, while the Ti layer could be seen over TG teeth that received TiF4 application. Conclusion: Under clinical circumstances, the 4% aqueous TiF4 solution was effective in preventing enamel mineral loss through increasing the enamel resistance to dental demineralization, enhancing its microhardness and fluoride uptake, and forming a Ti coat.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512023000100303&lng=en&tlng=enDental cariesDental enamelFluorides |
| spellingShingle | Ana Beatriz CHEVITARESE Karla Lorene de França LEITE Paulo Bechara DUTRA Matheus Melo PITHON Lucianne Cople Maia FARIA Antônio Carlos de Oliveira RUELLAS Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial Dental Press Journal of Orthodontics Dental caries Dental enamel Fluorides |
| title | Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial |
| title_full | Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial |
| title_fullStr | Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial |
| title_full_unstemmed | Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial |
| title_short | Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial |
| title_sort | effect of an aqueous 4 titanium tetrafluoride solution on preventing caries in orthodontic patients a controlled clinical trial |
| topic | Dental caries Dental enamel Fluorides |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512023000100303&lng=en&tlng=en |
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