Autofluorescence as a noninvasive biomarker of senescence and advanced glycation end products in Caenorhabditis elegans
Abstract To assess the utility of autofluorescence as a noninvasive biomarker of senescence in Caenorhabditis elegans, we measured the autofluorescence of individual nematodes using spectrofluorometry. The fluorescence of each worm increased with age. Animals with lower fluorescence intensity exhibi...
Main Authors: | Tomomi Komura, Mikihiro Yamanaka, Kohji Nishimura, Keita Hara, Yoshikazu Nishikawa |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-06-01
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Series: | npj Aging and Mechanisms of Disease |
Online Access: | https://doi.org/10.1038/s41514-021-00061-y |
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