Therapeutic Effect of CD4+CD25+ Regulatory T Cells Amplified In Vitro on Experimental Autoimmune Neuritis in Rats

Therapeutic Effect of CD4+CD25+ Regulatory T Cells Amplified In Vitro on Experimental Autoimmune Neuritis in Rats

Background/Aims: This study aimed to explore whether the adoptive transfusion of autologous CD4+CD25+ regulatory T cells (CD4+CD25+ Tregs) has a therapeutic effect on Experimental autoimmune neuritis (EAN) model rats, and it provides new experimental and theoretical bases for the immunotherapy of Gu...

Full description

Bibliographic Details
Main Authors:	Feng-Jie Wang, Dan Cui, Wei-Dong Qian
Format:	Article
Language:	English
Published:	Cell Physiol Biochem Press GmbH & Co KG 2018-05-01
Series:	Cellular Physiology and Biochemistry
Subjects:	Experimental autoimmune neuritis CD4+CD25+ regulatory T cells Immunomagnetic bead separation techniques Flow cytometry Adoptive transfusion
Online Access:	https://www.karger.com/Article/FullText/489919

Similar Items

Progress of CD8+CD25+regulatory T cells in diseases
by: WEN Li-na, CHEN Li, DUAN Rui, LI Fang
Published: (2022-12-01)

CD4+ CD25+ cells in type 1 diabetic patients with other autoimmune manifestations
by: Dalia S. Abd Elaziz, et al.
Published: (2014-11-01)

B cells play a cooperative role via CD40L–CD40 interaction in T cell-mediated experimental autoimmune neuritis in Lewis rats
by: Wei Zhu, et al.
Published: (2007-03-01)

Numerical status of CD4+CD25+FoxP3+ and CD8+CD28- regulatory T cells in multiple sclerosis
by: Ebrahim Kouchaki, et al.
Published: (2014-04-01)

CD4+CD25+Foxp3+ regulatory T cells: from basic research to potential therapeutic use
by: C Mottet, et al.
Published: (2007-11-01)

CD4+CD25+FOXP3+ Regulatory T Cells In Allogeneic Hematopoietic Cell Transplantation
by: Young-Ho Lee, et al.
Published: (2011-06-01)

Features of peripheral CD8+CD57+ lymphocytes in patients with autoimmune hemolytic anemia
by: Maria Celeste Fatone, et al.
Published: (2018-05-01)

Functional and Developmental Analysis of CD4+CD25+ Regulatory T Cells under the Influence of Streptococcal M Protein in Rheumatic Heart Disease
by: Nidhal Abdul-Auhaimen, et al.
Published: (2011-06-01)

Altered Frequencies of CD4+ CD25+ Foxp3+ and CD8+ CD25+ Foxp3+ Regulatory T Cells in Pre-eclampsia
by: Maryam Zare, et al.
Published: (2018-12-01)

Cyclosporin A-treated Dendritic Cells may affect the outcome of organ transplantation by decreasing CD4+CD25+ regulatory T cell proliferation
by: Karina Pino-Lagos, et al.
Published: (2010-01-01)

Enhanced glycolysis contributes to the pathogenesis of experimental autoimmune neuritis
by: Ru-Tao Liu, et al.
Published: (2018-02-01)

Alteration of CD4CD25Foxp3 T cell level in Kawasaki disease
by: Su Ye Sohn, et al.
Published: (2011-04-01)

A Two-Step Immunomagnetic Microbead-Based Method for the Isolation of Human Primary Skin Telocytes/CD34+ Stromal Cells
by: Eloisa Romano, et al.
Published: (2020-08-01)

CD4+CD25+ regulatory T cells ex vivo generated from autologous naïve CD4+ T cells suppress EAE progression
by: Ting-Ting Yang, et al.
Published: (2024-03-01)

Sel T Regulator CD4+CD25+ Mencegah Terjadinya Fenotip Letal pada Mencit Defisiensi CD122
by: Muhaimin Rifa’i, et al.
Published: (2012-11-01)

Intrathecal triamcinolone acetonide exerts anti-inflammatory effects on Lewis rat experimental autoimmune neuritis and direct anti-oxidative effects on Schwann cells
by: Kalliopi Pitarokoili, et al.
Published: (2019-03-01)

Quantitative analysis of CD4+CD25+FoxP3+ regulatory T-cells in canine atopic dermatitis in Korea
by: Dong-Jae Lee, et al.
Published: (2020-06-01)

Targeting the CD40-CD154 Signaling Pathway for Treatment of Autoimmune Arthritis
by: Jenn-Haung Lai, et al.
Published: (2019-08-01)

Integral membrane protein expression of human CD25 on the cell surface of HEK293 cell line: the available cellular model of CD25 positive to facilitate in vitro developing assays
by: Dehbashi Moein, et al.
Published: (2019-09-01)

ОСОБЕННОСТИ ДИНАМИКИ CD4+CD25+ СУБПОПУЛЯЦИЙ Т-ЛИМФОЦИТОВ ПАЦИЕНТОВ С УДОВЛЕТВОРИТЕЛЬНОЙ РАННЕЙ ФУНКЦИЕЙ ПОЧЕЧНОГО ТРАНСПЛАНТАТА
by: S. V. Zybleva, et al.
Published: (2021-05-01)

Kinesin-5 inhibition improves neural regeneration in experimental autoimmune neuritis
by: Felix Kohle, et al.
Published: (2023-06-01)

Efficient isolation of live microglia with preserved phenotypes from adult mouse brain
by: Nikodemova Maria, et al.
Published: (2012-06-01)

CD39+ REGULATORY T CELLS IN PULMONARY SARCOIDOSIS AND LOFGREN'S SYNDROME
by: Igor Vladimirovich Kudryavtsev, et al.
Published: (2019-03-01)

First report of expansion of CD4+/CD28 null T-helper lymphocytes in adult patients with idiopathic autoimmune hemolytic anemia
by: Soha R. Youssef, et al.
Published: (2021-10-01)

Prognostic value of CD25/CD123 pattern of expression in acute myeloid leukemia patients with normal cytogenetic
by: Salah Aref, et al.
Published: (2020-01-01)

The role of CD4+CD25+ regulatory T cells in macrophage-derived foam-cell formation
by: Jing Lin, et al.
Published: (2010-05-01)

Harnessing CD8<sup>+</sup>CD28<sup>−</sup> Regulatory T Cells as a Tool to Treat Autoimmune Disease
by: Sabrina Ceeraz, et al.
Published: (2021-11-01)

The role of regulatory CD4+CD25+high T-lymphocytes and their functional activity in the development of type 1 diabetes mellitus
by: Tatiana Vasil'evna Nikonova, et al.
Published: (2010-09-01)

Changes in Reactivity In Vitro of CD4+CD25+ and CD4+CD25− T Cell Subsets in Transplant Tolerance
by: Bruce M. Hall, et al.
Published: (2017-08-01)

Peran Penting Sel T Regulator CD8+CD25+FOXP3+ Menjaga Homeostasis Sel T pada Transplantasi Alogenik (ESSENTIAL ROLES OF CD8+CD25+FOXP3+ REGULATORY T CELLS IN THE MAINTENANCE OF T CELLS HOMEOSTASIS IN ALLOGENEIC TRANSPLANTATION)
by: Muhaimin Rifa’i, et al.
Published: (2013-12-01)

Peripheral CD4+CD25hiCD127low regulatory T cells are increased in patients with gastrointestinal cancer
by: Junlan Qiu, et al.
Published: (2023-05-01)

Evaluation of the Enzymatic Activity of Soluble CD13/APN and CD26/DPP4 in Serum and Urine Samples of Mice with Experimental Autoimmune Encephalomyelitis
by: Sanaz Mami, et al.
Published: (2021-11-01)

Interaction of peripheral CD4+CD25+CD127− Tregs with prolactin in HCV hepatocellular carcinoma: oncogenic or immunogenic mechanisms
by: Mona Abd El-Rahman Abu El-Makarem, et al.
Published: (2023-04-01)

Human CD4+CD25+CD226- Tregs Demonstrate Increased Purity, Lineage Stability, and Suppressive Capacity Versus CD4+CD25+CD127lo/- Tregs for Adoptive Cell Therapy
by: Matthew E. Brown, et al.
Published: (2022-05-01)

Level of Foxp3, DNMTs, methylation of Foxp3 promoter region, and CD4 + CD25 + CD127low regulatory T cells in vulvar lichen sclerosus
by: Lin Wang, et al.
Published: (2021-06-01)

Th17 cells and their cytokines serve as potential therapeutic target in experimental autoimmune neuritis
by: Shuping Liu, et al.
Published: (2019-12-01)

Peripheral Blood from Rheumatoid Arthritis Patients Shows Decreased T<sub>reg</sub> CD25 Expression and Reduced Frequency of Effector T<sub>reg</sub> Subpopulation
by: Eunbyeol Go, et al.
Published: (2021-04-01)

Tumor growth suppression by implantation of an anti-CD25 antibody-immobilized material near the tumor via regulatory T cell capture
by: Tsuyoshi Kimura, et al.
Published: (2021-12-01)

CD 4 + CD 25 + T cells maintain homeostasis by promoting TER - 119 cell development and inhibiting T cell activation
by: Muhaimin Rifa’i
Published: (2014-05-01)

CD25bright NK cells display superior function and metabolic activity under regulatory T cell-mediated suppression
by: Ziqing Chen, et al.
Published: (2023-12-01)