Fertility Sparing Treatment in Gastric-Type Endocervical Carcinoma

Fertility sparing management of cancer is one of the main components of quality-of-life issues. Early-stage cervical cancer, frequently diagnosed in women of reproductive age, can potentially be treated conservatively. However, some rare histological types of cervical cancer present with aggressive...

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Main Authors: Agnieszka Rychlik, Denis Querleu, Mariusz Bidzinski
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/20/5177
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author Agnieszka Rychlik
Denis Querleu
Mariusz Bidzinski
author_facet Agnieszka Rychlik
Denis Querleu
Mariusz Bidzinski
author_sort Agnieszka Rychlik
collection DOAJ
description Fertility sparing management of cancer is one of the main components of quality-of-life issues. Early-stage cervical cancer, frequently diagnosed in women of reproductive age, can potentially be treated conservatively. However, some rare histological types of cervical cancer present with aggressive clinical behavior. Particularly, in the newly introduced concept of gastric-type endocervical carcinoma, fertility sparing management is ‘a priori’ not recommended. Even so, this issue remains undocumented. For this reason, a selected review of the current literature on gastric type endocervical carcinoma was carried out through PubMed. The keywords included “gastric-type cervical cancer”, “gastric-type endocervical carcinoma”, “conservative surgery”, “conservative treatment”, “fertility sparing surgery”, “radical trachelectomy”, “laparoscopic trachelectomy”, “robotic trachelectomy”, “laparotomic trachelectomy”, “abdominal trachelectomy”, “trachelectomy”, “neoadjuvant chemotherapy”, “conisation”, and “cone resection”. A search in the European Network on Cancer, Infertility and Pregnancy (INCIP) database was performed. The rarity of gastric-type endocervical carcinoma does not allow for conclusions on fertility sparing management with solid evidence. However, diffuse character of the disease and aggressive clinical behavior contraindicate a conservative treatment in young women with gastric type cervical cancer.
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spelling doaj.art-940f036785c745a8a7ee006220ff81012023-11-22T17:41:32ZengMDPI AGCancers2072-66942021-10-011320517710.3390/cancers13205177Fertility Sparing Treatment in Gastric-Type Endocervical CarcinomaAgnieszka Rychlik0Denis Querleu1Mariusz Bidzinski2Department of Gynaecologic Oncology, National Research Institute of Oncology, 02-781 Warsaw, PolandDepartment of Obstetrics and Gynecology, University of Strasbourg, 67081 Strasbourg, FranceDepartment of Gynaecologic Oncology, National Research Institute of Oncology, 02-781 Warsaw, PolandFertility sparing management of cancer is one of the main components of quality-of-life issues. Early-stage cervical cancer, frequently diagnosed in women of reproductive age, can potentially be treated conservatively. However, some rare histological types of cervical cancer present with aggressive clinical behavior. Particularly, in the newly introduced concept of gastric-type endocervical carcinoma, fertility sparing management is ‘a priori’ not recommended. Even so, this issue remains undocumented. For this reason, a selected review of the current literature on gastric type endocervical carcinoma was carried out through PubMed. The keywords included “gastric-type cervical cancer”, “gastric-type endocervical carcinoma”, “conservative surgery”, “conservative treatment”, “fertility sparing surgery”, “radical trachelectomy”, “laparoscopic trachelectomy”, “robotic trachelectomy”, “laparotomic trachelectomy”, “abdominal trachelectomy”, “trachelectomy”, “neoadjuvant chemotherapy”, “conisation”, and “cone resection”. A search in the European Network on Cancer, Infertility and Pregnancy (INCIP) database was performed. The rarity of gastric-type endocervical carcinoma does not allow for conclusions on fertility sparing management with solid evidence. However, diffuse character of the disease and aggressive clinical behavior contraindicate a conservative treatment in young women with gastric type cervical cancer.https://www.mdpi.com/2072-6694/13/20/5177fertility sparing managementcervical cancergastric-type cervical cancer
spellingShingle Agnieszka Rychlik
Denis Querleu
Mariusz Bidzinski
Fertility Sparing Treatment in Gastric-Type Endocervical Carcinoma
Cancers
fertility sparing management
cervical cancer
gastric-type cervical cancer
title Fertility Sparing Treatment in Gastric-Type Endocervical Carcinoma
title_full Fertility Sparing Treatment in Gastric-Type Endocervical Carcinoma
title_fullStr Fertility Sparing Treatment in Gastric-Type Endocervical Carcinoma
title_full_unstemmed Fertility Sparing Treatment in Gastric-Type Endocervical Carcinoma
title_short Fertility Sparing Treatment in Gastric-Type Endocervical Carcinoma
title_sort fertility sparing treatment in gastric type endocervical carcinoma
topic fertility sparing management
cervical cancer
gastric-type cervical cancer
url https://www.mdpi.com/2072-6694/13/20/5177
work_keys_str_mv AT agnieszkarychlik fertilitysparingtreatmentingastrictypeendocervicalcarcinoma
AT denisquerleu fertilitysparingtreatmentingastrictypeendocervicalcarcinoma
AT mariuszbidzinski fertilitysparingtreatmentingastrictypeendocervicalcarcinoma