Intraocular Pressure Changes during Hemodiafiltration with Two different Concentrations of Sodium in the Dialysate
Ocular complications are common among end-stage renal disease patients and some complications had been linked to increments of intraocular pressure (IOP) during hemodialysis. The changes of IOP during hemodiafiltration (HDF) have been scarcely investigated and the potential influence of the sodium d...
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MDPI AG
2021-12-01
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| Online Access: | https://www.mdpi.com/2079-7737/11/1/12 |
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| author | Claudia Lerma Nadia Saavedra-Fuentes Jasbeth Ledesma-Gil Martín Calderón-Juárez Héctor Pérez-Grovas Salvador López-Gil |
| author_facet | Claudia Lerma Nadia Saavedra-Fuentes Jasbeth Ledesma-Gil Martín Calderón-Juárez Héctor Pérez-Grovas Salvador López-Gil |
| author_sort | Claudia Lerma |
| collection | DOAJ |
| description | Ocular complications are common among end-stage renal disease patients and some complications had been linked to increments of intraocular pressure (IOP) during hemodialysis. The changes of IOP during hemodiafiltration (HDF) have been scarcely investigated and the potential influence of the sodium dialysate concentration is unknown. The aim of this study was to compare the IOP changes during HDF with sodium dialysate concentration, either fixed or individualized. Thirteen end-stage renal disease patients participated in the study; they were treated with HDF using a dialysate sodium profile fixed at 138 mmol and another session with an individualized sodium profile. The intraocular pressure was measured before and after each session and every 30 min during HDF. Both groups had a similar HDF prescription, blood pressure, and biochemical parameters. At the end of hemodiafiltration, sodium concentration decreased only in the fixed sodium profile group. The number of patients with at least an episode of intraocular hypertension during HDF ranged from 5 (19%) to 8 (31%) without significant differences between right and left eye nor between dialysate sodium concentration. During HDF, there is a large variability of IOP; transient events of intraocular hypertension are highly prevalent in this sample, and they are not related to the sodium dialysate concentration. |
| first_indexed | 2024-03-10T01:54:08Z |
| format | Article |
| id | doaj.art-940f1432bd0d4a7da4498022da1c118e |
| institution | Directory Open Access Journal |
| issn | 2079-7737 |
| language | English |
| last_indexed | 2024-03-10T01:54:08Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biology |
| spelling | doaj.art-940f1432bd0d4a7da4498022da1c118e2023-11-23T12:59:41ZengMDPI AGBiology2079-77372021-12-011111210.3390/biology11010012Intraocular Pressure Changes during Hemodiafiltration with Two different Concentrations of Sodium in the DialysateClaudia Lerma0Nadia Saavedra-Fuentes1Jasbeth Ledesma-Gil2Martín Calderón-Juárez3Héctor Pérez-Grovas4Salvador López-Gil5Departamento de Instrumentación Electromecánica, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, MexicoDepartamento de Nefrología, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, MexicoDepartamento de Glaucoma, Instituto de Oftalmología Conde de la Valenciana, Mexico City 06800, MexicoDepartamento de Instrumentación Electromecánica, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, MexicoDepartamento de Nefrología, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, MexicoDepartamento de Nefrología, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, MexicoOcular complications are common among end-stage renal disease patients and some complications had been linked to increments of intraocular pressure (IOP) during hemodialysis. The changes of IOP during hemodiafiltration (HDF) have been scarcely investigated and the potential influence of the sodium dialysate concentration is unknown. The aim of this study was to compare the IOP changes during HDF with sodium dialysate concentration, either fixed or individualized. Thirteen end-stage renal disease patients participated in the study; they were treated with HDF using a dialysate sodium profile fixed at 138 mmol and another session with an individualized sodium profile. The intraocular pressure was measured before and after each session and every 30 min during HDF. Both groups had a similar HDF prescription, blood pressure, and biochemical parameters. At the end of hemodiafiltration, sodium concentration decreased only in the fixed sodium profile group. The number of patients with at least an episode of intraocular hypertension during HDF ranged from 5 (19%) to 8 (31%) without significant differences between right and left eye nor between dialysate sodium concentration. During HDF, there is a large variability of IOP; transient events of intraocular hypertension are highly prevalent in this sample, and they are not related to the sodium dialysate concentration.https://www.mdpi.com/2079-7737/11/1/12intraocular pressurehemodiafiltrationsodium concentrationintra-dialytic changes |
| spellingShingle | Claudia Lerma Nadia Saavedra-Fuentes Jasbeth Ledesma-Gil Martín Calderón-Juárez Héctor Pérez-Grovas Salvador López-Gil Intraocular Pressure Changes during Hemodiafiltration with Two different Concentrations of Sodium in the Dialysate Biology intraocular pressure hemodiafiltration sodium concentration intra-dialytic changes |
| title | Intraocular Pressure Changes during Hemodiafiltration with Two different Concentrations of Sodium in the Dialysate |
| title_full | Intraocular Pressure Changes during Hemodiafiltration with Two different Concentrations of Sodium in the Dialysate |
| title_fullStr | Intraocular Pressure Changes during Hemodiafiltration with Two different Concentrations of Sodium in the Dialysate |
| title_full_unstemmed | Intraocular Pressure Changes during Hemodiafiltration with Two different Concentrations of Sodium in the Dialysate |
| title_short | Intraocular Pressure Changes during Hemodiafiltration with Two different Concentrations of Sodium in the Dialysate |
| title_sort | intraocular pressure changes during hemodiafiltration with two different concentrations of sodium in the dialysate |
| topic | intraocular pressure hemodiafiltration sodium concentration intra-dialytic changes |
| url | https://www.mdpi.com/2079-7737/11/1/12 |
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