Correlation of fetal anterior abdominal wall thickness and other standard biometric ultrasound measurements to predict fetal macrosomia in gestational diabetes
Background: Gestational diabetes mellitus (GDM) is one of the most common medical conditions affecting pregnancy and significantly increasing the risk for maternal and perinatal complications. The aim of the present study is to study the correlation of fetal anterior abdominal wall thickness (FAAWT)...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Journal of Medical Ultrasound |
| Subjects: | |
| Online Access: | http://www.jmuonline.org/article.asp?issn=0929-6441;year=2023;volume=31;issue=1;spage=29;epage=34;aulast=Bansal |
| _version_ | 1827896543910297600 |
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| author | Ashish Bansal Brij Bhushan Thukral Neha Bagri Ankita Kanwar Ayush Khandelwal Bindu Bajaj |
| author_facet | Ashish Bansal Brij Bhushan Thukral Neha Bagri Ankita Kanwar Ayush Khandelwal Bindu Bajaj |
| author_sort | Ashish Bansal |
| collection | DOAJ |
| description | Background: Gestational diabetes mellitus (GDM) is one of the most common medical conditions affecting pregnancy and significantly increasing the risk for maternal and perinatal complications. The aim of the present study is to study the correlation of fetal anterior abdominal wall thickness (FAAWT) and other standard fetal biometric parameters measured by ultrasound between 36 and 39 weeks of gestation with neonatal birth weight in pregnancies complicated by GDM. Methods: Prospective cohort study in a tertiary care center including 100 singleton pregnancies with GDM were subjected to ultrasound between 36 and 39 weeks of gestation. Standard fetal biometry (Biparietal diameter, Head Circumference, Abdominal circumference [AC], and Femur Length) and estimated fetal weight were calculated. FAAWT was measured at AC section and actual neonatal birth weights were recorded after delivery. Macrosomia was defined as an absolute birth weight more than 4000 g regardless of the gestational age. Statistical analysis was done and 95% confidence level was considered significant. Results: Among 100 neonates, 16 were macrosomic (16%) and third trimester mean FAAWT was significantly higher in macrosomic babies (6.36 ± 0.5 mm) as compared to nonmacrosomic babies (5.54 ± 0.61 mm) (P < 0.0001). FAAWT >6 mm (Receiver operating characteristic curve derived) provided a sensitivity of 87.5%, specificity of 75%, positive predictive value of 40%, and negative predictive value (NPV) of 96.9% for prediction of macrosomia. While other standard fetal biometric parameters did not correlate well with actual birth weight in macrosomic neonates, only FAAWT was found to have statistically significant correlation (correlation coefficient of 0.626, P = 0.009). Conclusion: The FAAWT was the only sonographic parameter to have a significant correlation with neonatal birth weight in macrosomic neonates of GDM mothers. We found a high sensitivity (87.5%), specificity (75%), and NPV (96.9%) suggesting that FAAWT < 6 mm can rule out macrosomia in pregnancies with GDM. |
| first_indexed | 2024-03-12T22:36:37Z |
| format | Article |
| id | doaj.art-9411dfb52d2640459b9a5224562489d5 |
| institution | Directory Open Access Journal |
| issn | 0929-6441 2212-1552 |
| language | English |
| last_indexed | 2024-03-12T22:36:37Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Medical Ultrasound |
| spelling | doaj.art-9411dfb52d2640459b9a5224562489d52023-07-21T11:55:19ZengWolters Kluwer Medknow PublicationsJournal of Medical Ultrasound0929-64412212-15522023-01-01311293410.4103/JMU.JMU_57_21Correlation of fetal anterior abdominal wall thickness and other standard biometric ultrasound measurements to predict fetal macrosomia in gestational diabetesAshish BansalBrij Bhushan ThukralNeha BagriAnkita KanwarAyush KhandelwalBindu BajajBackground: Gestational diabetes mellitus (GDM) is one of the most common medical conditions affecting pregnancy and significantly increasing the risk for maternal and perinatal complications. The aim of the present study is to study the correlation of fetal anterior abdominal wall thickness (FAAWT) and other standard fetal biometric parameters measured by ultrasound between 36 and 39 weeks of gestation with neonatal birth weight in pregnancies complicated by GDM. Methods: Prospective cohort study in a tertiary care center including 100 singleton pregnancies with GDM were subjected to ultrasound between 36 and 39 weeks of gestation. Standard fetal biometry (Biparietal diameter, Head Circumference, Abdominal circumference [AC], and Femur Length) and estimated fetal weight were calculated. FAAWT was measured at AC section and actual neonatal birth weights were recorded after delivery. Macrosomia was defined as an absolute birth weight more than 4000 g regardless of the gestational age. Statistical analysis was done and 95% confidence level was considered significant. Results: Among 100 neonates, 16 were macrosomic (16%) and third trimester mean FAAWT was significantly higher in macrosomic babies (6.36 ± 0.5 mm) as compared to nonmacrosomic babies (5.54 ± 0.61 mm) (P < 0.0001). FAAWT >6 mm (Receiver operating characteristic curve derived) provided a sensitivity of 87.5%, specificity of 75%, positive predictive value of 40%, and negative predictive value (NPV) of 96.9% for prediction of macrosomia. While other standard fetal biometric parameters did not correlate well with actual birth weight in macrosomic neonates, only FAAWT was found to have statistically significant correlation (correlation coefficient of 0.626, P = 0.009). Conclusion: The FAAWT was the only sonographic parameter to have a significant correlation with neonatal birth weight in macrosomic neonates of GDM mothers. We found a high sensitivity (87.5%), specificity (75%), and NPV (96.9%) suggesting that FAAWT < 6 mm can rule out macrosomia in pregnancies with GDM.http://www.jmuonline.org/article.asp?issn=0929-6441;year=2023;volume=31;issue=1;spage=29;epage=34;aulast=Bansalanterior abdominal wall thicknessfetalgestational diabetes mellitusmacrosomiaultrasound |
| spellingShingle | Ashish Bansal Brij Bhushan Thukral Neha Bagri Ankita Kanwar Ayush Khandelwal Bindu Bajaj Correlation of fetal anterior abdominal wall thickness and other standard biometric ultrasound measurements to predict fetal macrosomia in gestational diabetes Journal of Medical Ultrasound anterior abdominal wall thickness fetal gestational diabetes mellitus macrosomia ultrasound |
| title | Correlation of fetal anterior abdominal wall thickness and other standard biometric ultrasound measurements to predict fetal macrosomia in gestational diabetes |
| title_full | Correlation of fetal anterior abdominal wall thickness and other standard biometric ultrasound measurements to predict fetal macrosomia in gestational diabetes |
| title_fullStr | Correlation of fetal anterior abdominal wall thickness and other standard biometric ultrasound measurements to predict fetal macrosomia in gestational diabetes |
| title_full_unstemmed | Correlation of fetal anterior abdominal wall thickness and other standard biometric ultrasound measurements to predict fetal macrosomia in gestational diabetes |
| title_short | Correlation of fetal anterior abdominal wall thickness and other standard biometric ultrasound measurements to predict fetal macrosomia in gestational diabetes |
| title_sort | correlation of fetal anterior abdominal wall thickness and other standard biometric ultrasound measurements to predict fetal macrosomia in gestational diabetes |
| topic | anterior abdominal wall thickness fetal gestational diabetes mellitus macrosomia ultrasound |
| url | http://www.jmuonline.org/article.asp?issn=0929-6441;year=2023;volume=31;issue=1;spage=29;epage=34;aulast=Bansal |
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