Behind the Adaptive and Resistance Mechanisms of Cancer Stem Cells to TRAIL

Behind the Adaptive and Resistance Mechanisms of Cancer Stem Cells to TRAIL

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand (Apo2L), is a member of the TNF cytokine superfamily. TRAIL has been widely studied as a novel strategy for tumor elimination, as cancer cells overexpress TRAIL death receptors, inducing apoptosis and i...

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Bibliographic Details
Main Authors: Adriana G. Quiroz-Reyes, Paulina Delgado-Gonzalez, Jose Francisco Islas, Juan Luis Delgado Gallegos, Javier Humberto Martínez Garza, Elsa N. Garza-Treviño
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceutics
Subjects:
TRAIL
cancer stem cells
TRAIL resistance
angiogenesis
Online Access:https://www.mdpi.com/1999-4923/13/7/1062

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