Establishing clinically meaningful within-individual improvement thresholds for eight patient-reported outcome measures in people with relapsing-remitting multiple sclerosis

Establishing clinically meaningful within-individual improvement thresholds for eight patient-reported outcome measures in people with relapsing-remitting multiple sclerosis

Abstract Background As disease-modifying therapies do not reverse the course of multiple sclerosis (MS), assessment of therapeutic success involves documenting patient-reported outcomes (PROs) concerning health-related quality of life, disease and treatment-related symptoms, and the impact of sympto...

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Bibliographic Details
Main Authors: Nupur Greene, Stéphane Quéré, Denise P. Bury, Flora Mazerolle, Manal M’Hari, Angély Loubert, Antoine Regnault, Keiko Higuchi
Format: Article
Language:English
Published: SpringerOpen 2023-07-01
Series:Journal of Patient-Reported Outcomes
Subjects:
Teriflunomide
Relapsing-remitting multiple sclerosis (RRMS)
Patient-reported outcome (PRO)
Validation
Within-patient change threshold
Online Access:https://doi.org/10.1186/s41687-023-00594-8

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