Evaluation of biometric indicators of anterior segment parameters after ICL implantation by swept-source optical coherence tomography
Abstract Background To evaluate anterior segment structural alterations after implantable collamer lens (ICL) implantation in myopic patients using swept-source quantitative optical coherence tomography (SS-OCT). Methods This prospective study included 47 eyes in 24 patients with preoperative spheri...
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BMC
2023-05-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-023-02942-0 |
| _version_ | 1797832171467046912 |
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| author | Chuhao Tang Tong Sun Zhengze Sun Hongyu Duan Yilin Liu Lu Zhao Wenlong Li Linbo Bian Hong Qi |
| author_facet | Chuhao Tang Tong Sun Zhengze Sun Hongyu Duan Yilin Liu Lu Zhao Wenlong Li Linbo Bian Hong Qi |
| author_sort | Chuhao Tang |
| collection | DOAJ |
| description | Abstract Background To evaluate anterior segment structural alterations after implantable collamer lens (ICL) implantation in myopic patients using swept-source quantitative optical coherence tomography (SS-OCT). Methods This prospective study included 47 eyes in 24 patients with preoperative spherical equivalent ≥ -3.00 D. Patients underwent ICL implantation at Department of Ophthalmology, Peking University Third Hospital, from May 2021 to December 2022. SS-OCT was used to measure anterior chamber width (ACW), angle opening distance (AOD), angle recess area (ARA), trabecular-iris area (TISA), trabecular-iris angle (TIA), iridotrabecular contact (ITC) area, and ITC Index before ICL implantation surgery and at 1 month follow-up. The correlations among the ITC index, vault, and angle parameters were analysed. Receiver operating characteristic (ROC) analysis was used to explore the ability of the vault to identify eyes with suspected angle-closure. Results At one month following ICL implantation, the ITC area was 0.396 ± 0.37 mm2, and the ITC index is 8.143 ± 5.439%. All angle parameters, except ACW, showed a statistically significant reduction on SS-OCT (P < 0.05). Mean AOD500, AOD750, ARA500, ARA750, TISA500, TISA750, TIA500, and TIA750 values at one month postoperatively decreased by 60.0%, 60.4%, 58.1%, 59.2%, 57.3%, 58.7%, 48.8%, and 50.7%, respectively. The vault was positively correlated with the ITC index and percent change in anterior chamber angle parameters. A vault of > 0.659 mm was found to be optimal for angle-closure suspect with a sensitivity of 85.2% and a specificity of 53.9%. Conclusions Anterior chamber angle parameters decreased one month after ICL implantation, and their percentage changes and ITC index correlated with the vault. When the vault is larger than 0.659 mm, it is necessary to be alert to possible closed angle suspicion. |
| first_indexed | 2024-04-09T14:03:29Z |
| format | Article |
| id | doaj.art-941bae0d22044c31aa9b2bb3f8545b90 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-04-09T14:03:29Z |
| publishDate | 2023-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-941bae0d22044c31aa9b2bb3f8545b902023-05-07T11:09:07ZengBMCBMC Ophthalmology1471-24152023-05-0123111010.1186/s12886-023-02942-0Evaluation of biometric indicators of anterior segment parameters after ICL implantation by swept-source optical coherence tomographyChuhao Tang0Tong Sun1Zhengze Sun2Hongyu Duan3Yilin Liu4Lu Zhao5Wenlong Li6Linbo Bian7Hong Qi8Department of Ophthalmology, Peking University Third Hospital, Beijing Key 9 Laboratory of Restoration of Damaged Ocular NerveDepartment of Ophthalmology, Peking University Third Hospital, Beijing Key 9 Laboratory of Restoration of Damaged Ocular NerveDepartment of Ophthalmology, Peking University Third Hospital, Beijing Key 9 Laboratory of Restoration of Damaged Ocular NerveDepartment of Ophthalmology, Peking University Third Hospital, Beijing Key 9 Laboratory of Restoration of Damaged Ocular NerveDepartment of Ophthalmology, Peking University Third Hospital, Beijing Key 9 Laboratory of Restoration of Damaged Ocular NerveDepartment of Ophthalmology, Peking University Third Hospital, Beijing Key 9 Laboratory of Restoration of Damaged Ocular NerveDepartment of Ophthalmology, Peking University Third Hospital, Beijing Key 9 Laboratory of Restoration of Damaged Ocular NerveDepartment of Ophthalmology, Peking University Third Hospital, Beijing Key 9 Laboratory of Restoration of Damaged Ocular NerveDepartment of Ophthalmology, Peking University Third Hospital, Beijing Key 9 Laboratory of Restoration of Damaged Ocular NerveAbstract Background To evaluate anterior segment structural alterations after implantable collamer lens (ICL) implantation in myopic patients using swept-source quantitative optical coherence tomography (SS-OCT). Methods This prospective study included 47 eyes in 24 patients with preoperative spherical equivalent ≥ -3.00 D. Patients underwent ICL implantation at Department of Ophthalmology, Peking University Third Hospital, from May 2021 to December 2022. SS-OCT was used to measure anterior chamber width (ACW), angle opening distance (AOD), angle recess area (ARA), trabecular-iris area (TISA), trabecular-iris angle (TIA), iridotrabecular contact (ITC) area, and ITC Index before ICL implantation surgery and at 1 month follow-up. The correlations among the ITC index, vault, and angle parameters were analysed. Receiver operating characteristic (ROC) analysis was used to explore the ability of the vault to identify eyes with suspected angle-closure. Results At one month following ICL implantation, the ITC area was 0.396 ± 0.37 mm2, and the ITC index is 8.143 ± 5.439%. All angle parameters, except ACW, showed a statistically significant reduction on SS-OCT (P < 0.05). Mean AOD500, AOD750, ARA500, ARA750, TISA500, TISA750, TIA500, and TIA750 values at one month postoperatively decreased by 60.0%, 60.4%, 58.1%, 59.2%, 57.3%, 58.7%, 48.8%, and 50.7%, respectively. The vault was positively correlated with the ITC index and percent change in anterior chamber angle parameters. A vault of > 0.659 mm was found to be optimal for angle-closure suspect with a sensitivity of 85.2% and a specificity of 53.9%. Conclusions Anterior chamber angle parameters decreased one month after ICL implantation, and their percentage changes and ITC index correlated with the vault. When the vault is larger than 0.659 mm, it is necessary to be alert to possible closed angle suspicion.https://doi.org/10.1186/s12886-023-02942-0Implantable collamer lens implantation surgeryMyopiaOptical coherence tomographyVaultIridotrabecular contact |
| spellingShingle | Chuhao Tang Tong Sun Zhengze Sun Hongyu Duan Yilin Liu Lu Zhao Wenlong Li Linbo Bian Hong Qi Evaluation of biometric indicators of anterior segment parameters after ICL implantation by swept-source optical coherence tomography BMC Ophthalmology Implantable collamer lens implantation surgery Myopia Optical coherence tomography Vault Iridotrabecular contact |
| title | Evaluation of biometric indicators of anterior segment parameters after ICL implantation by swept-source optical coherence tomography |
| title_full | Evaluation of biometric indicators of anterior segment parameters after ICL implantation by swept-source optical coherence tomography |
| title_fullStr | Evaluation of biometric indicators of anterior segment parameters after ICL implantation by swept-source optical coherence tomography |
| title_full_unstemmed | Evaluation of biometric indicators of anterior segment parameters after ICL implantation by swept-source optical coherence tomography |
| title_short | Evaluation of biometric indicators of anterior segment parameters after ICL implantation by swept-source optical coherence tomography |
| title_sort | evaluation of biometric indicators of anterior segment parameters after icl implantation by swept source optical coherence tomography |
| topic | Implantable collamer lens implantation surgery Myopia Optical coherence tomography Vault Iridotrabecular contact |
| url | https://doi.org/10.1186/s12886-023-02942-0 |
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