Hydrophobicity and charge shape cellular metabolite concentrations.

Hydrophobicity and charge shape cellular metabolite concentrations.

What governs the concentrations of metabolites within living cells? Beyond specific metabolic and enzymatic considerations, are there global trends that affect their values? We hypothesize that the physico-chemical properties of metabolites considerably affect their in-vivo concentrations. The recen...

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Bibliographic Details
Main Authors: Arren Bar-Even, Elad Noor, Avi Flamholz, Joerg M Buescher, Ron Milo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21998563/pdf/?tool=EBI

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