Ginsenoside Rg1 interferes with the progression of diabetic osteoporosis by promoting type H angiogenesis modulating vasculogenic and osteogenic coupling

Ginsenoside Rg1 interferes with the progression of diabetic osteoporosis by promoting type H angiogenesis modulating vasculogenic and osteogenic coupling

Ginsenoside Rg1 (Rg1) has been demonstrated to have antidiabetic and antiosteoporotic activities. The aim of this study was to investigate the protective effect of Rg1 against diabetic osteoporosis and the underlying mechanism. In vitro, we found that Rg1 increased the number of osteoprogenitors and...

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Bibliographic Details
Main Authors: Wenhui Chen, Xinyan Jin, Ting Wang, Rui Bai, Jun Shi, Yunxia Jiang, Simin Tan, Ruijie Wu, Shiqi Zeng, Hongxiang Zheng, Hongyang Jia, Shuanglei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
type H vessels
Notch
Noggin
VEGF
diabetic osteoporosis
angiogenic-osteogenic coupling
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1010937/full

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