Differential neurophysiological correlates of information processing in Internet gaming disorder and alcohol use disorder measured by event-related potentials
Abstract Internet gaming disorder (IGD) shares clinical and neuropsychological features with alcohol use disorder (AUD), but few studies have identified the neurophysiological characteristics of IGD. We investigated the N100 and P300 event-related potentials (ERPs) in patients with IGD to compare th...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-08-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-017-09679-z |
| _version_ | 1818684962599075840 |
|---|---|
| author | Minkyung Park Yeon Jin Kim Dai Jin Kim Jung-Seok Choi |
| author_facet | Minkyung Park Yeon Jin Kim Dai Jin Kim Jung-Seok Choi |
| author_sort | Minkyung Park |
| collection | DOAJ |
| description | Abstract Internet gaming disorder (IGD) shares clinical and neuropsychological features with alcohol use disorder (AUD), but few studies have identified the neurophysiological characteristics of IGD. We investigated the N100 and P300 event-related potentials (ERPs) in patients with IGD to compare them with those of patients with AUD and healthy controls (HCs). Twenty-six patients with IGD, 22 patients with AUD, and 29 HCs participated in this study. ERPs were acquired from young male adults during an auditory oddball task. Between-group differences in N100 and P300 were investigated separately using repeated-measures analysis of variance. Correlations between the ERP values and neurocognitive functioning of each group were examined. Both the IGD and AUD groups showed reduced P300 amplitudes at the midline central and parietal area compared with the HCs. The IGD exhibited reduced N100 amplitudes at the midline frontal area compared with the HCs. The reduced P300 were correlated with a higher spatial span error rate in the IGD. The reduced N100 and P300 were not correlated with Internet addiction severity scores in the IGD. These results indicate that IGD have abnormalities in the P300 comparable to those in AUD. Moreover, the reduction in N100 could be considered a candidate trait marker for IGD. |
| first_indexed | 2024-12-17T10:58:58Z |
| format | Article |
| id | doaj.art-9421378db396438bb36c3580dec2f839 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-17T10:58:58Z |
| publishDate | 2017-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-9421378db396438bb36c3580dec2f8392022-12-21T21:51:45ZengNature PortfolioScientific Reports2045-23222017-08-01711810.1038/s41598-017-09679-zDifferential neurophysiological correlates of information processing in Internet gaming disorder and alcohol use disorder measured by event-related potentialsMinkyung Park0Yeon Jin Kim1Dai Jin Kim2Jung-Seok Choi3Department of Psychiatry, SMG-SNU Boramae Medical CenterDepartment of Psychiatry, SMG-SNU Boramae Medical CenterDepartment of Psychiatry, Seoul St. Mary’s Hospital, The Catholic University of Korea College of MedicineDepartment of Psychiatry, SMG-SNU Boramae Medical CenterAbstract Internet gaming disorder (IGD) shares clinical and neuropsychological features with alcohol use disorder (AUD), but few studies have identified the neurophysiological characteristics of IGD. We investigated the N100 and P300 event-related potentials (ERPs) in patients with IGD to compare them with those of patients with AUD and healthy controls (HCs). Twenty-six patients with IGD, 22 patients with AUD, and 29 HCs participated in this study. ERPs were acquired from young male adults during an auditory oddball task. Between-group differences in N100 and P300 were investigated separately using repeated-measures analysis of variance. Correlations between the ERP values and neurocognitive functioning of each group were examined. Both the IGD and AUD groups showed reduced P300 amplitudes at the midline central and parietal area compared with the HCs. The IGD exhibited reduced N100 amplitudes at the midline frontal area compared with the HCs. The reduced P300 were correlated with a higher spatial span error rate in the IGD. The reduced N100 and P300 were not correlated with Internet addiction severity scores in the IGD. These results indicate that IGD have abnormalities in the P300 comparable to those in AUD. Moreover, the reduction in N100 could be considered a candidate trait marker for IGD.https://doi.org/10.1038/s41598-017-09679-z |
| spellingShingle | Minkyung Park Yeon Jin Kim Dai Jin Kim Jung-Seok Choi Differential neurophysiological correlates of information processing in Internet gaming disorder and alcohol use disorder measured by event-related potentials Scientific Reports |
| title | Differential neurophysiological correlates of information processing in Internet gaming disorder and alcohol use disorder measured by event-related potentials |
| title_full | Differential neurophysiological correlates of information processing in Internet gaming disorder and alcohol use disorder measured by event-related potentials |
| title_fullStr | Differential neurophysiological correlates of information processing in Internet gaming disorder and alcohol use disorder measured by event-related potentials |
| title_full_unstemmed | Differential neurophysiological correlates of information processing in Internet gaming disorder and alcohol use disorder measured by event-related potentials |
| title_short | Differential neurophysiological correlates of information processing in Internet gaming disorder and alcohol use disorder measured by event-related potentials |
| title_sort | differential neurophysiological correlates of information processing in internet gaming disorder and alcohol use disorder measured by event related potentials |
| url | https://doi.org/10.1038/s41598-017-09679-z |
| work_keys_str_mv | AT minkyungpark differentialneurophysiologicalcorrelatesofinformationprocessingininternetgamingdisorderandalcoholusedisordermeasuredbyeventrelatedpotentials AT yeonjinkim differentialneurophysiologicalcorrelatesofinformationprocessingininternetgamingdisorderandalcoholusedisordermeasuredbyeventrelatedpotentials AT daijinkim differentialneurophysiologicalcorrelatesofinformationprocessingininternetgamingdisorderandalcoholusedisordermeasuredbyeventrelatedpotentials AT jungseokchoi differentialneurophysiologicalcorrelatesofinformationprocessingininternetgamingdisorderandalcoholusedisordermeasuredbyeventrelatedpotentials |