Miopericarditis autoinflamatoria aguda recurrente: de la fisiopatología a la clínica.
Recurrent myopericarditis is the acute inflammation of the pericardium and myocardium that relapses after a symptom-free interval of 4 to 6 weeks. A thorough differential diagnosis is necessary to identify uncommon causes that may have therapeutic and prognostic importance. These include autoinflamm...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sociedade Galega de Medicina Interna
2022-12-01
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| Series: | Galicia Clínica |
| Subjects: | |
| Online Access: | https://galiciaclinica.info/publicacion.asp?f=2643 |
| _version_ | 1797945206480306176 |
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| author | Yoana Besteiro Balado Juan Carlos Piñeiro Fernández Andrea López López |
| author_facet | Yoana Besteiro Balado Juan Carlos Piñeiro Fernández Andrea López López |
| author_sort | Yoana Besteiro Balado |
| collection | DOAJ |
| description | Recurrent myopericarditis is the acute inflammation of the pericardium and myocardium that relapses after a symptom-free interval of 4 to 6 weeks. A thorough differential diagnosis is necessary to identify uncommon causes that may have therapeutic and prognostic importance. These include autoinflammatory diseases, which can present as recurrent myopericarditis in genetically predisposed or impaired-immunity individuals.
We present a 33-year-old male with polyclonal hypogammaglobulinemia and six episodes of myopericarditis, in which the diagnosis of a probable autoinflammatory syndrome was established. Targeted treatment based on the pathophysiological mechanismswas started with immunoglobulins and anakinra, with favourable clinical and serological outcome with no relapses.
Organ-specific autoinflammatory diseases with myocardial involvement may be associated with life-threatening complications. The role of multidisciplinary care and a diagnostic approach focused on the pathophysiology of the disease could be the most important thing for early treatment to improve the prognosis and quality of life of our patients. |
| first_indexed | 2024-04-10T20:52:36Z |
| format | Article |
| id | doaj.art-9425d46b7bf548d49c691c30a8675300 |
| institution | Directory Open Access Journal |
| issn | 0304-4866 1989-3922 |
| language | English |
| last_indexed | 2024-04-10T20:52:36Z |
| publishDate | 2022-12-01 |
| publisher | Sociedade Galega de Medicina Interna |
| record_format | Article |
| series | Galicia Clínica |
| spelling | doaj.art-9425d46b7bf548d49c691c30a86753002023-01-23T09:15:37ZengSociedade Galega de Medicina InternaGalicia Clínica0304-48661989-39222022-12-01834525510.22546/67/26432643Miopericarditis autoinflamatoria aguda recurrente: de la fisiopatología a la clínica.Yoana Besteiro Balado0Juan Carlos Piñeiro Fernández1Andrea López López2Servicio de Medicina Interna. Hospital Universitario Lucus Augusti.Servicio de Medicina Interna. Hospital Universitario Lucus Augusti.Servicio de Cardiología. Hospital Universitario Lucus Augusti.Recurrent myopericarditis is the acute inflammation of the pericardium and myocardium that relapses after a symptom-free interval of 4 to 6 weeks. A thorough differential diagnosis is necessary to identify uncommon causes that may have therapeutic and prognostic importance. These include autoinflammatory diseases, which can present as recurrent myopericarditis in genetically predisposed or impaired-immunity individuals. We present a 33-year-old male with polyclonal hypogammaglobulinemia and six episodes of myopericarditis, in which the diagnosis of a probable autoinflammatory syndrome was established. Targeted treatment based on the pathophysiological mechanismswas started with immunoglobulins and anakinra, with favourable clinical and serological outcome with no relapses. Organ-specific autoinflammatory diseases with myocardial involvement may be associated with life-threatening complications. The role of multidisciplinary care and a diagnostic approach focused on the pathophysiology of the disease could be the most important thing for early treatment to improve the prognosis and quality of life of our patients.https://galiciaclinica.info/publicacion.asp?f=2643miocarditispericarditisenfermedades autoinflamatoriasinflamasomaanakinra |
| spellingShingle | Yoana Besteiro Balado Juan Carlos Piñeiro Fernández Andrea López López Miopericarditis autoinflamatoria aguda recurrente: de la fisiopatología a la clínica. Galicia Clínica miocarditis pericarditis enfermedades autoinflamatorias inflamasoma anakinra |
| title | Miopericarditis autoinflamatoria aguda recurrente: de la fisiopatología a la clínica. |
| title_full | Miopericarditis autoinflamatoria aguda recurrente: de la fisiopatología a la clínica. |
| title_fullStr | Miopericarditis autoinflamatoria aguda recurrente: de la fisiopatología a la clínica. |
| title_full_unstemmed | Miopericarditis autoinflamatoria aguda recurrente: de la fisiopatología a la clínica. |
| title_short | Miopericarditis autoinflamatoria aguda recurrente: de la fisiopatología a la clínica. |
| title_sort | miopericarditis autoinflamatoria aguda recurrente de la fisiopatologia a la clinica |
| topic | miocarditis pericarditis enfermedades autoinflamatorias inflamasoma anakinra |
| url | https://galiciaclinica.info/publicacion.asp?f=2643 |
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