Squalamine and Its Aminosterol Derivatives: Overview of Biological Effects and Mechanisms of Action of Compounds with Multiple Therapeutic Applications

Squalamine is a natural aminosterol that has been discovered in the tissues of the dogfish shark (<i>Squalus acanthias</i>). Studies have previously demonstrated that this promoter compound and its derivatives exhibit potent bactericidal activity against Gram-negative, Gram-positive bact...

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Bibliographic Details
Main Authors: Nour Mammari, Elsa Salles, Audrey Beaussart, Sofiane El-Kirat-Chatel, Mihayl Varbanov
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/10/6/1205