Vocalization–whisking coordination and multisensory integration of social signals in rat auditory cortex
Social interactions involve multi-modal signaling. Here, we study interacting rats to investigate audio-haptic coordination and multisensory integration in the auditory cortex. We find that facial touch is associated with an increased rate of ultrasonic vocalizations, which are emitted at the whiski...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2014-12-01
|
| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/03185 |
| _version_ | 1818018939345567744 |
|---|---|
| author | Rajnish P Rao Falk Mielke Evgeny Bobrov Michael Brecht |
| author_facet | Rajnish P Rao Falk Mielke Evgeny Bobrov Michael Brecht |
| author_sort | Rajnish P Rao |
| collection | DOAJ |
| description | Social interactions involve multi-modal signaling. Here, we study interacting rats to investigate audio-haptic coordination and multisensory integration in the auditory cortex. We find that facial touch is associated with an increased rate of ultrasonic vocalizations, which are emitted at the whisking rate (∼8 Hz) and preferentially initiated in the retraction phase of whisking. In a small subset of auditory cortex regular-spiking neurons, we observed excitatory and heterogeneous responses to ultrasonic vocalizations. Most fast-spiking neurons showed a stronger response to calls. Interestingly, facial touch-induced inhibition in the primary auditory cortex and off-responses after termination of touch were twofold stronger than responses to vocalizations. Further, touch modulated the responsiveness of auditory cortex neurons to ultrasonic vocalizations. In summary, facial touch during social interactions involves precisely orchestrated calling-whisking patterns. While ultrasonic vocalizations elicited a rather weak population response from the regular spikers, the modulation of neuronal responses by facial touch was remarkably strong. |
| first_indexed | 2024-04-14T07:46:15Z |
| format | Article |
| id | doaj.art-942aa2e35d8143b99f9cd4640d3a4cb4 |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-04-14T07:46:15Z |
| publishDate | 2014-12-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-942aa2e35d8143b99f9cd4640d3a4cb42022-12-22T02:05:20ZengeLife Sciences Publications LtdeLife2050-084X2014-12-01310.7554/eLife.03185Vocalization–whisking coordination and multisensory integration of social signals in rat auditory cortexRajnish P Rao0Falk Mielke1Evgeny Bobrov2Michael Brecht3Bernstein Center for Computational Neuroscience, Humboldt University of Berlin, Berlin, GermanyBernstein Center for Computational Neuroscience, Humboldt University of Berlin, Berlin, GermanyBernstein Center for Computational Neuroscience, Humboldt University of Berlin, Berlin, Germany; Berlin School of Mind and Brain, Humboldt University of Berlin, Berlin, GermanyBernstein Center for Computational Neuroscience, Humboldt University of Berlin, Berlin, GermanySocial interactions involve multi-modal signaling. Here, we study interacting rats to investigate audio-haptic coordination and multisensory integration in the auditory cortex. We find that facial touch is associated with an increased rate of ultrasonic vocalizations, which are emitted at the whisking rate (∼8 Hz) and preferentially initiated in the retraction phase of whisking. In a small subset of auditory cortex regular-spiking neurons, we observed excitatory and heterogeneous responses to ultrasonic vocalizations. Most fast-spiking neurons showed a stronger response to calls. Interestingly, facial touch-induced inhibition in the primary auditory cortex and off-responses after termination of touch were twofold stronger than responses to vocalizations. Further, touch modulated the responsiveness of auditory cortex neurons to ultrasonic vocalizations. In summary, facial touch during social interactions involves precisely orchestrated calling-whisking patterns. While ultrasonic vocalizations elicited a rather weak population response from the regular spikers, the modulation of neuronal responses by facial touch was remarkably strong.https://elifesciences.org/articles/03185whiskingultrasonic vocalizationsocial interactionfacial touchauditory cortexmultisensory integration |
| spellingShingle | Rajnish P Rao Falk Mielke Evgeny Bobrov Michael Brecht Vocalization–whisking coordination and multisensory integration of social signals in rat auditory cortex eLife whisking ultrasonic vocalization social interaction facial touch auditory cortex multisensory integration |
| title | Vocalization–whisking coordination and multisensory integration of social signals in rat auditory cortex |
| title_full | Vocalization–whisking coordination and multisensory integration of social signals in rat auditory cortex |
| title_fullStr | Vocalization–whisking coordination and multisensory integration of social signals in rat auditory cortex |
| title_full_unstemmed | Vocalization–whisking coordination and multisensory integration of social signals in rat auditory cortex |
| title_short | Vocalization–whisking coordination and multisensory integration of social signals in rat auditory cortex |
| title_sort | vocalization whisking coordination and multisensory integration of social signals in rat auditory cortex |
| topic | whisking ultrasonic vocalization social interaction facial touch auditory cortex multisensory integration |
| url | https://elifesciences.org/articles/03185 |
| work_keys_str_mv | AT rajnishprao vocalizationwhiskingcoordinationandmultisensoryintegrationofsocialsignalsinratauditorycortex AT falkmielke vocalizationwhiskingcoordinationandmultisensoryintegrationofsocialsignalsinratauditorycortex AT evgenybobrov vocalizationwhiskingcoordinationandmultisensoryintegrationofsocialsignalsinratauditorycortex AT michaelbrecht vocalizationwhiskingcoordinationandmultisensoryintegrationofsocialsignalsinratauditorycortex |