Current Updates in Bleomycin-Based Electrochemotherapy for Deep-Seated Soft-Tissue Tumors
Electrochemotherapy (ECT) has evolved significantly during the last decade, expanding treatment indications from superficial skin lesions to advanced-stage, deep-seated tumors in hard-to-reach areas. Electrodes have also shown steady technological improvement throughout the years. Besides standard a...
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| Format: | Article |
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MDPI AG
2023-05-01
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| Series: | Electrochem |
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| Online Access: | https://www.mdpi.com/2673-3293/4/2/19 |
| _version_ | 1827737676582748160 |
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| author | Aurel Ottlakan Gyorgy Lazar Judit Olah Andras Nagy Gabor Vass Marton Vas Raissa Pereira Erika Kis |
| author_facet | Aurel Ottlakan Gyorgy Lazar Judit Olah Andras Nagy Gabor Vass Marton Vas Raissa Pereira Erika Kis |
| author_sort | Aurel Ottlakan |
| collection | DOAJ |
| description | Electrochemotherapy (ECT) has evolved significantly during the last decade, expanding treatment indications from superficial skin lesions to advanced-stage, deep-seated tumors in hard-to-reach areas. Electrodes have also shown steady technological improvement throughout the years. Besides standard and VEG (variable geometry electrode) electrodes, the introduction of laparoscopic electrodes has brought on a new era in ECT treatment, making the minimally invasive approach a reality. The exact role of ECT in the oncological dashboard is yet to be determined; however, increased tumor response, pain relief, and a low number of adverse events may yield the way for more widespread application of the technique with possible further inclusion of ECT in international oncological guidelines. The aim of this review is to give an overview on the current status of ECT in deep-seated tumor treatment and shed light on its emerging role in local anticancer therapy. |
| first_indexed | 2024-03-11T02:32:50Z |
| format | Article |
| id | doaj.art-94304e05748d4e17be28863e70da42d0 |
| institution | Directory Open Access Journal |
| issn | 2673-3293 |
| language | English |
| last_indexed | 2024-03-11T02:32:50Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Electrochem |
| spelling | doaj.art-94304e05748d4e17be28863e70da42d02023-11-18T10:07:18ZengMDPI AGElectrochem2673-32932023-05-014228229010.3390/electrochem4020019Current Updates in Bleomycin-Based Electrochemotherapy for Deep-Seated Soft-Tissue TumorsAurel Ottlakan0Gyorgy Lazar1Judit Olah2Andras Nagy3Gabor Vass4Marton Vas5Raissa Pereira6Erika Kis7Department of Surgery, University of Szeged, Semmelweis Str. 8, 6720 Szeged, HungaryDepartment of Surgery, University of Szeged, Semmelweis Str. 8, 6720 Szeged, HungaryDepartment of Oncotherapy, University of Szeged, Koranyi Alley 12, 6720 Szeged, HungaryDepartment of Radiology, University of Szeged, 6720 Szeged, HungaryDepartment of Dermatology and Allergology, University of Szeged, Koranyi Alley 6, 6720 Szeged, HungaryDepartment of Surgery, University of Szeged, Semmelweis Str. 8, 6720 Szeged, HungaryDepartment of Surgery, University of Szeged, Semmelweis Str. 8, 6720 Szeged, HungaryDepartment of Dermatology and Allergology, University of Szeged, Koranyi Alley 6, 6720 Szeged, HungaryElectrochemotherapy (ECT) has evolved significantly during the last decade, expanding treatment indications from superficial skin lesions to advanced-stage, deep-seated tumors in hard-to-reach areas. Electrodes have also shown steady technological improvement throughout the years. Besides standard and VEG (variable geometry electrode) electrodes, the introduction of laparoscopic electrodes has brought on a new era in ECT treatment, making the minimally invasive approach a reality. The exact role of ECT in the oncological dashboard is yet to be determined; however, increased tumor response, pain relief, and a low number of adverse events may yield the way for more widespread application of the technique with possible further inclusion of ECT in international oncological guidelines. The aim of this review is to give an overview on the current status of ECT in deep-seated tumor treatment and shed light on its emerging role in local anticancer therapy.https://www.mdpi.com/2673-3293/4/2/19electrochemotherapybleomycindeep-seated tumorpain reliefvariable electrode geometry |
| spellingShingle | Aurel Ottlakan Gyorgy Lazar Judit Olah Andras Nagy Gabor Vass Marton Vas Raissa Pereira Erika Kis Current Updates in Bleomycin-Based Electrochemotherapy for Deep-Seated Soft-Tissue Tumors Electrochem electrochemotherapy bleomycin deep-seated tumor pain relief variable electrode geometry |
| title | Current Updates in Bleomycin-Based Electrochemotherapy for Deep-Seated Soft-Tissue Tumors |
| title_full | Current Updates in Bleomycin-Based Electrochemotherapy for Deep-Seated Soft-Tissue Tumors |
| title_fullStr | Current Updates in Bleomycin-Based Electrochemotherapy for Deep-Seated Soft-Tissue Tumors |
| title_full_unstemmed | Current Updates in Bleomycin-Based Electrochemotherapy for Deep-Seated Soft-Tissue Tumors |
| title_short | Current Updates in Bleomycin-Based Electrochemotherapy for Deep-Seated Soft-Tissue Tumors |
| title_sort | current updates in bleomycin based electrochemotherapy for deep seated soft tissue tumors |
| topic | electrochemotherapy bleomycin deep-seated tumor pain relief variable electrode geometry |
| url | https://www.mdpi.com/2673-3293/4/2/19 |
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