Vascular medicine and thrombectomy in stroke

The treatment of stroke caused by intracranial vessel occlusion with intravenous recombinant tissue plasminogen activator (rt-PA) was the only evidence-based treatment option for a long time. Nevertheless the response rate was disappointing in large vessel occlusions. Five studies that evaluated the...

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Main Authors: Sebastian Fischer, Werner Weber
Format: Article
Language:English
Published: SAGE Publishing 2018-01-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/1756285617742082
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author Sebastian Fischer
Werner Weber
author_facet Sebastian Fischer
Werner Weber
author_sort Sebastian Fischer
collection DOAJ
description The treatment of stroke caused by intracranial vessel occlusion with intravenous recombinant tissue plasminogen activator (rt-PA) was the only evidence-based treatment option for a long time. Nevertheless the response rate was disappointing in large vessel occlusions. Five studies that evaluated the efficacy of mechanical thrombectomy published in 2015 proved a significant clinical benefit for selected patients suffering from acute ischemic stroke. These results are the basis for extensive technical, institutional, and personal structural changes in the neurovascular field of stroke treatment. This review gives an overview of the current status of mechanical thrombectomy and future expectations and challenges are discussed.
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spelling doaj.art-9434c9aaf64f45e1ba02f26bfe4808712022-12-22T01:55:46ZengSAGE PublishingTherapeutic Advances in Neurological Disorders1756-28642018-01-011110.1177/1756285617742082Vascular medicine and thrombectomy in strokeSebastian FischerWerner WeberThe treatment of stroke caused by intracranial vessel occlusion with intravenous recombinant tissue plasminogen activator (rt-PA) was the only evidence-based treatment option for a long time. Nevertheless the response rate was disappointing in large vessel occlusions. Five studies that evaluated the efficacy of mechanical thrombectomy published in 2015 proved a significant clinical benefit for selected patients suffering from acute ischemic stroke. These results are the basis for extensive technical, institutional, and personal structural changes in the neurovascular field of stroke treatment. This review gives an overview of the current status of mechanical thrombectomy and future expectations and challenges are discussed.https://doi.org/10.1177/1756285617742082
spellingShingle Sebastian Fischer
Werner Weber
Vascular medicine and thrombectomy in stroke
Therapeutic Advances in Neurological Disorders
title Vascular medicine and thrombectomy in stroke
title_full Vascular medicine and thrombectomy in stroke
title_fullStr Vascular medicine and thrombectomy in stroke
title_full_unstemmed Vascular medicine and thrombectomy in stroke
title_short Vascular medicine and thrombectomy in stroke
title_sort vascular medicine and thrombectomy in stroke
url https://doi.org/10.1177/1756285617742082
work_keys_str_mv AT sebastianfischer vascularmedicineandthrombectomyinstroke
AT wernerweber vascularmedicineandthrombectomyinstroke