Diagnosis and management of eosinophilic granuloma of the jaw: a case report
The eosinophilic granuloma is the most common form of the Langherans’ cell histiocytosis. In the majority of cases it is represented by a unilocular osteolytic lesion which can occur in adults and children. It is an intraosseous destructive lesion characterized by the presence of vast numbers of eos...
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| Format: | Article |
| Language: | English |
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Faculdade São Leopoldo Mandic
2019-06-01
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| Series: | RGO: Revista Gaúcha de Odontologia |
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| Online Access: | https://www.scielo.br/scielo.php?script=sci_arttext&pid=S1981-86372019000100807&lng=en&nrm=iso&tlng=en |
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| author | Marcos Vinícius Mendes DANTAS Paloma Beatriz Rosa Nunes de SOUZA Marisa Aparecida Cabrini GABRIELLI |
| author_facet | Marcos Vinícius Mendes DANTAS Paloma Beatriz Rosa Nunes de SOUZA Marisa Aparecida Cabrini GABRIELLI |
| author_sort | Marcos Vinícius Mendes DANTAS |
| collection | DOAJ |
| description | The eosinophilic granuloma is the most common form of the Langherans’ cell histiocytosis. In the majority of cases it is represented by a unilocular osteolytic lesion which can occur in adults and children. It is an intraosseous destructive lesion characterized by the presence of vast numbers of eosinophils and histiocytes. It can be localized or multifocal. The tumor is more prevalent in the first two decades of life and tends to affect mandibular body and angle. Most frequent signs and symptoms are pain, swelling, ulceration, gingival necrosis, alveolar bone destruction with mobility and loss of teeth. Therapeutic interventions for this pathology are surgical curettage, local radiotherapy and chemotherapy. This article presents the case of a 9-year old patient who came in for treatment with facial swelling, pain, tooth mobility and intraoral ulcer in the vestibular sulcus of the right mandibular angle region. Imaging and incisional biopsy were obtained. After the histopathological examination confirmed the diagnosis of eosinophilic granuloma, the lesion was removed by curettage and a reconstruction titanium plate was inserted to avoid a pathological fracture. After 14 years of follow-up no recurrence was found and mandibular growth was not impaired. A discussion about this type of tumor is presented, based on the current literature. |
| first_indexed | 2024-12-10T21:39:12Z |
| format | Article |
| id | doaj.art-9438e3836e47458e974f5a70d397c3d7 |
| institution | Directory Open Access Journal |
| issn | 1981-8637 |
| language | English |
| last_indexed | 2024-12-10T21:39:12Z |
| publishDate | 2019-06-01 |
| publisher | Faculdade São Leopoldo Mandic |
| record_format | Article |
| series | RGO: Revista Gaúcha de Odontologia |
| spelling | doaj.art-9438e3836e47458e974f5a70d397c3d72022-12-22T01:32:34ZengFaculdade São Leopoldo MandicRGO: Revista Gaúcha de Odontologia1981-86372019-06-0167e20190029http://dx.doi.org/10.1590/1981-86372019000293576Diagnosis and management of eosinophilic granuloma of the jaw: a case reportMarcos Vinícius Mendes DANTAS0https://orcid.org/0000-0002-4427-5941Paloma Beatriz Rosa Nunes de SOUZA1https://orcid.org/0000-0002-1052-9042Marisa Aparecida Cabrini GABRIELLI2https://orcid.org/0000-0002-7147-1438Universidade Estadual Paulista, Faculdade de Odontologia de Araraquara, Departamento de Diagnóstico e CirurgiaUniversidade Estadual Paulista, Faculdade de Odontologia de Araraquara, Departamento de Diagnóstico e CirurgiaUniversidade Estadual Paulista, Faculdade de Odontologia de Araraquara, Departamento de Diagnóstico e CirurgiaThe eosinophilic granuloma is the most common form of the Langherans’ cell histiocytosis. In the majority of cases it is represented by a unilocular osteolytic lesion which can occur in adults and children. It is an intraosseous destructive lesion characterized by the presence of vast numbers of eosinophils and histiocytes. It can be localized or multifocal. The tumor is more prevalent in the first two decades of life and tends to affect mandibular body and angle. Most frequent signs and symptoms are pain, swelling, ulceration, gingival necrosis, alveolar bone destruction with mobility and loss of teeth. Therapeutic interventions for this pathology are surgical curettage, local radiotherapy and chemotherapy. This article presents the case of a 9-year old patient who came in for treatment with facial swelling, pain, tooth mobility and intraoral ulcer in the vestibular sulcus of the right mandibular angle region. Imaging and incisional biopsy were obtained. After the histopathological examination confirmed the diagnosis of eosinophilic granuloma, the lesion was removed by curettage and a reconstruction titanium plate was inserted to avoid a pathological fracture. After 14 years of follow-up no recurrence was found and mandibular growth was not impaired. A discussion about this type of tumor is presented, based on the current literature.https://www.scielo.br/scielo.php?script=sci_arttext&pid=S1981-86372019000100807&lng=en&nrm=iso&tlng=encurettage. eosinophilic granulom. langerhans cell histiocytosis |
| spellingShingle | Marcos Vinícius Mendes DANTAS Paloma Beatriz Rosa Nunes de SOUZA Marisa Aparecida Cabrini GABRIELLI Diagnosis and management of eosinophilic granuloma of the jaw: a case report RGO: Revista Gaúcha de Odontologia curettage. eosinophilic granulom. langerhans cell histiocytosis |
| title | Diagnosis and management of eosinophilic granuloma of the jaw: a case report |
| title_full | Diagnosis and management of eosinophilic granuloma of the jaw: a case report |
| title_fullStr | Diagnosis and management of eosinophilic granuloma of the jaw: a case report |
| title_full_unstemmed | Diagnosis and management of eosinophilic granuloma of the jaw: a case report |
| title_short | Diagnosis and management of eosinophilic granuloma of the jaw: a case report |
| title_sort | diagnosis and management of eosinophilic granuloma of the jaw a case report |
| topic | curettage. eosinophilic granulom. langerhans cell histiocytosis |
| url | https://www.scielo.br/scielo.php?script=sci_arttext&pid=S1981-86372019000100807&lng=en&nrm=iso&tlng=en |
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