Estimation of Cardiorespiratory Fitness Without Exercise Testing: Cross-Validation in Midlife and Older Women

Background: Cardiorespiratory fitness (CRF) is associated with important health risk outcomes, including the development of Type 2 diabetes and cardiovascular disease. Measures of maximal or peak oxygen consumption (VO2) are the typical criterion methods for determining CRF; however, in clinical set...

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Main Authors: Jody L. Clasey, Anita M. Adams, Paul J. Geiger, Suzanne C. Segerstrom, Leslie J. Crofford
Format: Article
Language:English
Published: Mary Ann Liebert 2020-12-01
Series:Women's Health Reports
Subjects:
Online Access:https://www.liebertpub.com/doi/full/10.1089/WHR.2020.0045
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author Jody L. Clasey
Anita M. Adams
Paul J. Geiger
Suzanne C. Segerstrom
Leslie J. Crofford
author_facet Jody L. Clasey
Anita M. Adams
Paul J. Geiger
Suzanne C. Segerstrom
Leslie J. Crofford
author_sort Jody L. Clasey
collection DOAJ
description Background: Cardiorespiratory fitness (CRF) is associated with important health risk outcomes, including the development of Type 2 diabetes and cardiovascular disease. Measures of maximal or peak oxygen consumption (VO2) are the typical criterion methods for determining CRF; however, in clinical settings, these measures are impractical. Methods: We validated a clinically derived estimate of CRF against predicted maximal VO2 in a sample of healthy, midlife and older adult women (n?=?188). Women completed a clinic evaluation (including treadmill testing), daily diaries about their physical activity, and additional clinical scales. Two models were tested. The first model calculated estimated cardiorespiratory fitness (eCRF) using assigned weights and regressed eCRF on predicted cardiorespiratory fitness (pCRF). The second model used sample-specific, empirical weights. Both models were tested twice, once with retrospective and once with daily diary physical activity reports. Results: The model accounted for 34% of the variance in pCRF when using assigned weights and 41% of the variance in pCRF when using empirical weights. For age, body mass index, and resting heart rate, assigned and estimated weights were similar, but estimates for physical activity differed. There was little improvement in model fit between retrospective and daily diary measurements of physical activity when either assigned (R2?=?0.32) or fitted weights (R2?=?0.40) were used. Conclusions: Midlife and older women's CRF can be estimated from routinely collected clinical measures, demonstrating their utility.
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spelling doaj.art-9439f119168b4878ab2a92b51110c0082024-01-26T05:31:19ZengMary Ann LiebertWomen's Health Reports2688-48442020-12-011158459110.1089/WHR.2020.0045Estimation of Cardiorespiratory Fitness Without Exercise Testing: Cross-Validation in Midlife and Older WomenJody L. ClaseyAnita M. AdamsPaul J. GeigerSuzanne C. SegerstromLeslie J. CroffordBackground: Cardiorespiratory fitness (CRF) is associated with important health risk outcomes, including the development of Type 2 diabetes and cardiovascular disease. Measures of maximal or peak oxygen consumption (VO2) are the typical criterion methods for determining CRF; however, in clinical settings, these measures are impractical. Methods: We validated a clinically derived estimate of CRF against predicted maximal VO2 in a sample of healthy, midlife and older adult women (n?=?188). Women completed a clinic evaluation (including treadmill testing), daily diaries about their physical activity, and additional clinical scales. Two models were tested. The first model calculated estimated cardiorespiratory fitness (eCRF) using assigned weights and regressed eCRF on predicted cardiorespiratory fitness (pCRF). The second model used sample-specific, empirical weights. Both models were tested twice, once with retrospective and once with daily diary physical activity reports. Results: The model accounted for 34% of the variance in pCRF when using assigned weights and 41% of the variance in pCRF when using empirical weights. For age, body mass index, and resting heart rate, assigned and estimated weights were similar, but estimates for physical activity differed. There was little improvement in model fit between retrospective and daily diary measurements of physical activity when either assigned (R2?=?0.32) or fitted weights (R2?=?0.40) were used. Conclusions: Midlife and older women's CRF can be estimated from routinely collected clinical measures, demonstrating their utility.https://www.liebertpub.com/doi/full/10.1089/WHR.2020.0045cardiorespiratory fitness (CRF)physical activitywomen's health
spellingShingle Jody L. Clasey
Anita M. Adams
Paul J. Geiger
Suzanne C. Segerstrom
Leslie J. Crofford
Estimation of Cardiorespiratory Fitness Without Exercise Testing: Cross-Validation in Midlife and Older Women
Women's Health Reports
cardiorespiratory fitness (CRF)
physical activity
women's health
title Estimation of Cardiorespiratory Fitness Without Exercise Testing: Cross-Validation in Midlife and Older Women
title_full Estimation of Cardiorespiratory Fitness Without Exercise Testing: Cross-Validation in Midlife and Older Women
title_fullStr Estimation of Cardiorespiratory Fitness Without Exercise Testing: Cross-Validation in Midlife and Older Women
title_full_unstemmed Estimation of Cardiorespiratory Fitness Without Exercise Testing: Cross-Validation in Midlife and Older Women
title_short Estimation of Cardiorespiratory Fitness Without Exercise Testing: Cross-Validation in Midlife and Older Women
title_sort estimation of cardiorespiratory fitness without exercise testing cross validation in midlife and older women
topic cardiorespiratory fitness (CRF)
physical activity
women's health
url https://www.liebertpub.com/doi/full/10.1089/WHR.2020.0045
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