The KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD): A Korean Chronic Kidney Disease Cohort
The KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD) was launched in 2011 with the support of the Korea Disease Control and Prevention Agency. The study was designed with the aim of exploring the various clinical features and characteristics of chronic kidney disea...
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Format: | Article |
Language: | English |
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Korean Society for Preventive Medicine
2022-07-01
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Series: | Journal of Preventive Medicine and Public Health |
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Online Access: | http://jpmph.org/upload/pdf/jpmph-22-031.pdf |
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author | Kook-Hwan Oh Sue K. Park Jayoun Kim Curie Ahn Representing the KNOW-CKD Study Investigators |
author_facet | Kook-Hwan Oh Sue K. Park Jayoun Kim Curie Ahn Representing the KNOW-CKD Study Investigators |
author_sort | Kook-Hwan Oh |
collection | DOAJ |
description | The KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD) was launched in 2011 with the support of the Korea Disease Control and Prevention Agency. The study was designed with the aim of exploring the various clinical features and characteristics of chronic kidney disease (CKD) in Koreans, and elucidating the risk factors for CKD progression and adverse outcomes of CKD. For the cohort study, nephrologists at 9 tertiary university-affiliated hospitals participated in patient recruitment and follow-up. Biostatisticians and epidemiologists also participated in the basic design and structuring of the study. From 2011 until 2016, the KNOW-CKD Phase I recruited 2238 adult patients with CKD from stages G1 to G5, who were not receiving renal replacement therapy. The KNOW-CKD Phase II recruitment was started in 2019, with an enrollment target of 1500 subjects, focused on diabetic nephropathy and hypertensive kidney diseases in patients with reduced kidney function who are presumed to be at a higher risk of adverse outcomes. As of 2021, the KNOW-CKD investigators have published articles in the fields of socioeconomics, quality of life, nutrition, physical activity, renal progression, cardiovascular disease and outcomes, anemia, mineral bone disease, serum and urine biomarkers, and international and inter-ethnic comparisons. The KNOW-CKD researchers will elaborate a prediction model for various outcomes of CKD such as the development of end-stage kidney disease, major adverse cardiovascular events, and death. |
first_indexed | 2024-12-10T17:15:03Z |
format | Article |
id | doaj.art-943aee4f5c0f4d2b91ff464a8e2bcb15 |
institution | Directory Open Access Journal |
issn | 1975-8375 2233-4521 |
language | English |
last_indexed | 2024-12-10T17:15:03Z |
publishDate | 2022-07-01 |
publisher | Korean Society for Preventive Medicine |
record_format | Article |
series | Journal of Preventive Medicine and Public Health |
spelling | doaj.art-943aee4f5c0f4d2b91ff464a8e2bcb152022-12-22T01:40:09ZengKorean Society for Preventive MedicineJournal of Preventive Medicine and Public Health1975-83752233-45212022-07-0155431332010.3961/jpmph.22.0312233The KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD): A Korean Chronic Kidney Disease CohortKook-Hwan Oh0Sue K. Park1Jayoun Kim2Curie Ahn3Representing the KNOW-CKD Study Investigators Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Korea Department of Internal Medicine, National Medical Center, Seoul, KoreaThe KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD) was launched in 2011 with the support of the Korea Disease Control and Prevention Agency. The study was designed with the aim of exploring the various clinical features and characteristics of chronic kidney disease (CKD) in Koreans, and elucidating the risk factors for CKD progression and adverse outcomes of CKD. For the cohort study, nephrologists at 9 tertiary university-affiliated hospitals participated in patient recruitment and follow-up. Biostatisticians and epidemiologists also participated in the basic design and structuring of the study. From 2011 until 2016, the KNOW-CKD Phase I recruited 2238 adult patients with CKD from stages G1 to G5, who were not receiving renal replacement therapy. The KNOW-CKD Phase II recruitment was started in 2019, with an enrollment target of 1500 subjects, focused on diabetic nephropathy and hypertensive kidney diseases in patients with reduced kidney function who are presumed to be at a higher risk of adverse outcomes. As of 2021, the KNOW-CKD investigators have published articles in the fields of socioeconomics, quality of life, nutrition, physical activity, renal progression, cardiovascular disease and outcomes, anemia, mineral bone disease, serum and urine biomarkers, and international and inter-ethnic comparisons. The KNOW-CKD researchers will elaborate a prediction model for various outcomes of CKD such as the development of end-stage kidney disease, major adverse cardiovascular events, and death.http://jpmph.org/upload/pdf/jpmph-22-031.pdfchronic kidney diseaseknow-ckdcohortoutcome |
spellingShingle | Kook-Hwan Oh Sue K. Park Jayoun Kim Curie Ahn Representing the KNOW-CKD Study Investigators The KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD): A Korean Chronic Kidney Disease Cohort Journal of Preventive Medicine and Public Health chronic kidney disease know-ckd cohort outcome |
title | The KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD): A Korean Chronic Kidney Disease Cohort |
title_full | The KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD): A Korean Chronic Kidney Disease Cohort |
title_fullStr | The KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD): A Korean Chronic Kidney Disease Cohort |
title_full_unstemmed | The KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD): A Korean Chronic Kidney Disease Cohort |
title_short | The KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD): A Korean Chronic Kidney Disease Cohort |
title_sort | korean cohort study for outcomes in patients with chronic kidney disease know ckd a korean chronic kidney disease cohort |
topic | chronic kidney disease know-ckd cohort outcome |
url | http://jpmph.org/upload/pdf/jpmph-22-031.pdf |
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