Probiotic-Based Bacteriocin: Immunity Supplementation Against Viruses. An Updated Review
Viral infections are a major cause of severe, fatal diseases worldwide. Recently, these infections have increased due to demanding contextual circumstances, such as environmental changes, increased migration of people and product distribution, rapid demographic changes, and outbreaks of novel viruse...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-07-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2022.876058/full |
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| author | Muhammad Umair Muhammad Umair Saqib Jabbar Lu Zhaoxin Zhang Jianhao Muhammad Abid Kashif-Ur R. Khan Sameh A. Korma Mashail A. Alghamdi Mohamed T. El-Saadony Mohamed E. Abd El-Hack Ilaria Cacciotti Synan F. AbuQamar Khaled A. El-Tarabily Khaled A. El-Tarabily Khaled A. El-Tarabily Liqing Zhao Liqing Zhao |
| author_facet | Muhammad Umair Muhammad Umair Saqib Jabbar Lu Zhaoxin Zhang Jianhao Muhammad Abid Kashif-Ur R. Khan Sameh A. Korma Mashail A. Alghamdi Mohamed T. El-Saadony Mohamed E. Abd El-Hack Ilaria Cacciotti Synan F. AbuQamar Khaled A. El-Tarabily Khaled A. El-Tarabily Khaled A. El-Tarabily Liqing Zhao Liqing Zhao |
| author_sort | Muhammad Umair |
| collection | DOAJ |
| description | Viral infections are a major cause of severe, fatal diseases worldwide. Recently, these infections have increased due to demanding contextual circumstances, such as environmental changes, increased migration of people and product distribution, rapid demographic changes, and outbreaks of novel viruses, including the COVID-19 outbreak. Internal variables that influence viral immunity have received attention along with these external causes to avert such novel viral outbreaks. The gastrointestinal microbiome (GIM), particularly the present probiotics, plays a vital role in the host immune system by mediating host protective immunity and acting as an immune regulator. Bacteriocins possess numerous health benefits and exhibit antagonistic activity against enteric pathogens and immunobiotics, thereby inhibiting viral infections. Moreover, disrupting the homeostasis of the GIM/host immune system negatively affects viral immunity. The interactions between bacteriocins and infectious viruses, particularly in COVID-19, through improved host immunity and physiology are complex and have not yet been studied, although several studies have proven that bacteriocins influence the outcomes of viral infections. However, the complex transmission to the affected sites and siRNA defense against nuclease digestion lead to challenging clinical trials. Additionally, bacteriocins are well known for their biofunctional properties and underlying mechanisms in the treatment of bacterial and fungal infections. However, few studies have shown the role of probiotics-derived bacteriocin against viral infections. Thus, based on the results of the previous studies, this review lays out a road map for future studies on bacteriocins for treating viral infections. |
| first_indexed | 2024-04-13T09:35:49Z |
| format | Article |
| id | doaj.art-943fdd0743b34cdd9a24048d4c653c22 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-04-13T09:35:49Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-943fdd0743b34cdd9a24048d4c653c222022-12-22T02:52:06ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2022-07-011310.3389/fmicb.2022.876058876058Probiotic-Based Bacteriocin: Immunity Supplementation Against Viruses. An Updated ReviewMuhammad Umair0Muhammad Umair1Saqib Jabbar2Lu Zhaoxin3Zhang Jianhao4Muhammad Abid5Kashif-Ur R. Khan6Sameh A. Korma7Mashail A. Alghamdi8Mohamed T. El-Saadony9Mohamed E. Abd El-Hack10Ilaria Cacciotti11Synan F. AbuQamar12Khaled A. El-Tarabily13Khaled A. El-Tarabily14Khaled A. El-Tarabily15Liqing Zhao16Liqing Zhao17Department of Food Science and Engineering, College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, ChinaKey Laboratory of Optoelectronic Devices and Systems, College of Physics and Optoelectronic Engineering, Ministry of Education and Guangdong Province, Shenzhen University, Shenzhen, ChinaFood Science Research Institute (FSRI), National Agricultural Research Centre (NARC), Islamabad, PakistanCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing, ChinaCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing, ChinaInstitute of Food and Nutritional Sciences, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, PakistanDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, PakistanDepartment of Food Science, Faculty of Agriculture, Zagazig University, Zagazig, EgyptDepartment of Biology, Faculty of Science, King Abdulaziz University, Jeddah, Saudi ArabiaDepartment of Agricultural Microbiology, Faculty of Agriculture, Zagazig University, Zagazig, Egypt0Department of Poultry, Faculty of Agriculture, Zagazig University, Zagazig, Egypt1Department of Engineering, INSTM RU, University of Rome “Niccolò Cusano”, Rome, Italy2Department of Biology, College of Science, United Arab Emirates University, Al-Ain, United Arab Emirates2Department of Biology, College of Science, United Arab Emirates University, Al-Ain, United Arab Emirates3Khalifa Center for Genetic Engineering and Biotechnology, United Arab Emirates University, Al-Ain, United Arab Emirates4Harry Butler Institute, Murdoch University, Murdoch, WA, AustraliaDepartment of Food Science and Engineering, College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, ChinaKey Laboratory of Optoelectronic Devices and Systems, College of Physics and Optoelectronic Engineering, Ministry of Education and Guangdong Province, Shenzhen University, Shenzhen, ChinaViral infections are a major cause of severe, fatal diseases worldwide. Recently, these infections have increased due to demanding contextual circumstances, such as environmental changes, increased migration of people and product distribution, rapid demographic changes, and outbreaks of novel viruses, including the COVID-19 outbreak. Internal variables that influence viral immunity have received attention along with these external causes to avert such novel viral outbreaks. The gastrointestinal microbiome (GIM), particularly the present probiotics, plays a vital role in the host immune system by mediating host protective immunity and acting as an immune regulator. Bacteriocins possess numerous health benefits and exhibit antagonistic activity against enteric pathogens and immunobiotics, thereby inhibiting viral infections. Moreover, disrupting the homeostasis of the GIM/host immune system negatively affects viral immunity. The interactions between bacteriocins and infectious viruses, particularly in COVID-19, through improved host immunity and physiology are complex and have not yet been studied, although several studies have proven that bacteriocins influence the outcomes of viral infections. However, the complex transmission to the affected sites and siRNA defense against nuclease digestion lead to challenging clinical trials. Additionally, bacteriocins are well known for their biofunctional properties and underlying mechanisms in the treatment of bacterial and fungal infections. However, few studies have shown the role of probiotics-derived bacteriocin against viral infections. Thus, based on the results of the previous studies, this review lays out a road map for future studies on bacteriocins for treating viral infections.https://www.frontiersin.org/articles/10.3389/fmicb.2022.876058/fullantiviral immunitybacteriocinimmune interactionimmunomodulatoryprobioticsviral infection |
| spellingShingle | Muhammad Umair Muhammad Umair Saqib Jabbar Lu Zhaoxin Zhang Jianhao Muhammad Abid Kashif-Ur R. Khan Sameh A. Korma Mashail A. Alghamdi Mohamed T. El-Saadony Mohamed E. Abd El-Hack Ilaria Cacciotti Synan F. AbuQamar Khaled A. El-Tarabily Khaled A. El-Tarabily Khaled A. El-Tarabily Liqing Zhao Liqing Zhao Probiotic-Based Bacteriocin: Immunity Supplementation Against Viruses. An Updated Review Frontiers in Microbiology antiviral immunity bacteriocin immune interaction immunomodulatory probiotics viral infection |
| title | Probiotic-Based Bacteriocin: Immunity Supplementation Against Viruses. An Updated Review |
| title_full | Probiotic-Based Bacteriocin: Immunity Supplementation Against Viruses. An Updated Review |
| title_fullStr | Probiotic-Based Bacteriocin: Immunity Supplementation Against Viruses. An Updated Review |
| title_full_unstemmed | Probiotic-Based Bacteriocin: Immunity Supplementation Against Viruses. An Updated Review |
| title_short | Probiotic-Based Bacteriocin: Immunity Supplementation Against Viruses. An Updated Review |
| title_sort | probiotic based bacteriocin immunity supplementation against viruses an updated review |
| topic | antiviral immunity bacteriocin immune interaction immunomodulatory probiotics viral infection |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2022.876058/full |
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