Fusobacterium nucleatum triggers proinflammatory cell death via Z-DNA binding protein 1 in apical periodontitis

Fusobacterium nucleatum triggers proinflammatory cell death via Z-DNA binding protein 1 in apical periodontitis

Abstract Background Z-DNA binding protein 1 (ZBP1) is a vital innate immune sensor that regulates inflammation during pathogen invasion. ZBP1 may contribute to pyroptosis, apoptosis and necroptosis in infectious diseases. In this study, Fusobacterium nucleatum (F. nucleatum) infection caused periapi...

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Bibliographic Details
Main Authors: Hui Liu, Yuxuan Liu, Wei Fan, Bing Fan
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cell Communication and Signaling
Subjects:
Z-DNA binding protein 1
Fusobacterium nucleatum
Extracellular vesicles
Cell death
Apical periodontitis
Online Access:https://doi.org/10.1186/s12964-022-01005-z

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