Sperm parameters and anti-Müllerian hormone remain stable with Helicobacter pylori infection: a cross-sectional study
Abstract Background and aims It has been reported that Helicobacter pylori (HP) infection was more prevalent in infertile populations. HP infection could lead to decreased sperm parameters, and treating the HP infection could improve the quality of sperm. However, studies investigating the relations...
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| Format: | Article |
| Language: | English |
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BMC
2020-11-01
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| Series: | BMC Urology |
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| Online Access: | http://link.springer.com/article/10.1186/s12894-020-00725-z |
| _version_ | 1818322758569820160 |
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| author | Chun Feng Ping-Ping Lv Chang-Chang Huang Song-Qing Yang Qiu-Ping Yao Jin-Ming Shen Min Jin |
| author_facet | Chun Feng Ping-Ping Lv Chang-Chang Huang Song-Qing Yang Qiu-Ping Yao Jin-Ming Shen Min Jin |
| author_sort | Chun Feng |
| collection | DOAJ |
| description | Abstract Background and aims It has been reported that Helicobacter pylori (HP) infection was more prevalent in infertile populations. HP infection could lead to decreased sperm parameters, and treating the HP infection could improve the quality of sperm. However, studies investigating the relationship between infertility and HP infection are still limited, and more evidence is required. Therefore, we performed the present study to investigate the impact of HP infection on sperm quality in males and on ovarian reserve in females. Methods A total of 16,522 patients who visited the Second Hospital of Zhejiang University from January 2016 to June 2019 due to abdominal discomfort and underwent a 13/14C-urea breath HP test were included in this retrospective cross-sectional study. Among them, 565 had performed sperm analysis or ovarian reserve tests in the past three months and were involved for further analyses. Sperm parameters were examined with a computer-assisted sperm analysis system, and serum anti-Müllerian hormone (AMH) and sex hormones were tested with an electrochemiluminescence method. Results Among 363 patients who underwent the sperm test, 136 (37.47%) had HP infection. Among 202 patients who underwent the AMH test, 55 (27.23%) had HP infection. There was no difference in sperm concentration and motility between the HP+ and HP− groups (P > 0.05). Further subgroup analyses stratified into 5-year age groups confirmed that there was no significant difference in sperm parameters (P > 0.05). When pooled with previously published data, no significant difference in sperm concentration or motility was found (P > 0.05). Meanwhile, this study found that the serum AMH level was similar between the HP+ and HP− groups (P > 0.05). Further subgroup analyses confirmed that there was no significant difference in serum AMH level (P > 0.05). Conclusions There were no differences in sperm parameters and AMH levels based on history of HP infection among Chinese patients. |
| first_indexed | 2024-12-13T11:01:53Z |
| format | Article |
| id | doaj.art-944e1783e1db4f1b8bcc8cc27b58ce34 |
| institution | Directory Open Access Journal |
| issn | 1471-2490 |
| language | English |
| last_indexed | 2024-12-13T11:01:53Z |
| publishDate | 2020-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Urology |
| spelling | doaj.art-944e1783e1db4f1b8bcc8cc27b58ce342022-12-21T23:49:13ZengBMCBMC Urology1471-24902020-11-012011910.1186/s12894-020-00725-zSperm parameters and anti-Müllerian hormone remain stable with Helicobacter pylori infection: a cross-sectional studyChun Feng0Ping-Ping Lv1Chang-Chang Huang2Song-Qing Yang3Qiu-Ping Yao4Jin-Ming Shen5Min Jin6Department of Reproductive Medicine, The Second Affiliated Hospital of Zhejiang University School of MedicineThe Women’s Hospital of Zhejiang University School of MedicineDepartment of Reproductive Medicine, The Second Affiliated Hospital of Zhejiang University School of MedicineDepartment of Reproductive Medicine, The Second Affiliated Hospital of Zhejiang University School of MedicineDepartment of Reproductive Medicine, The Second Affiliated Hospital of Zhejiang University School of MedicineDepartment of Orthopedics, The First Affiliated Hospital of Zhejiang Chinese Medicine UniversityDepartment of Reproductive Medicine, The Second Affiliated Hospital of Zhejiang University School of MedicineAbstract Background and aims It has been reported that Helicobacter pylori (HP) infection was more prevalent in infertile populations. HP infection could lead to decreased sperm parameters, and treating the HP infection could improve the quality of sperm. However, studies investigating the relationship between infertility and HP infection are still limited, and more evidence is required. Therefore, we performed the present study to investigate the impact of HP infection on sperm quality in males and on ovarian reserve in females. Methods A total of 16,522 patients who visited the Second Hospital of Zhejiang University from January 2016 to June 2019 due to abdominal discomfort and underwent a 13/14C-urea breath HP test were included in this retrospective cross-sectional study. Among them, 565 had performed sperm analysis or ovarian reserve tests in the past three months and were involved for further analyses. Sperm parameters were examined with a computer-assisted sperm analysis system, and serum anti-Müllerian hormone (AMH) and sex hormones were tested with an electrochemiluminescence method. Results Among 363 patients who underwent the sperm test, 136 (37.47%) had HP infection. Among 202 patients who underwent the AMH test, 55 (27.23%) had HP infection. There was no difference in sperm concentration and motility between the HP+ and HP− groups (P > 0.05). Further subgroup analyses stratified into 5-year age groups confirmed that there was no significant difference in sperm parameters (P > 0.05). When pooled with previously published data, no significant difference in sperm concentration or motility was found (P > 0.05). Meanwhile, this study found that the serum AMH level was similar between the HP+ and HP− groups (P > 0.05). Further subgroup analyses confirmed that there was no significant difference in serum AMH level (P > 0.05). Conclusions There were no differences in sperm parameters and AMH levels based on history of HP infection among Chinese patients.http://link.springer.com/article/10.1186/s12894-020-00725-zHelicobacter pylori (HP)Anti-müllerian hormone (AMH)Sperm parametersProgressive motility |
| spellingShingle | Chun Feng Ping-Ping Lv Chang-Chang Huang Song-Qing Yang Qiu-Ping Yao Jin-Ming Shen Min Jin Sperm parameters and anti-Müllerian hormone remain stable with Helicobacter pylori infection: a cross-sectional study BMC Urology Helicobacter pylori (HP) Anti-müllerian hormone (AMH) Sperm parameters Progressive motility |
| title | Sperm parameters and anti-Müllerian hormone remain stable with Helicobacter pylori infection: a cross-sectional study |
| title_full | Sperm parameters and anti-Müllerian hormone remain stable with Helicobacter pylori infection: a cross-sectional study |
| title_fullStr | Sperm parameters and anti-Müllerian hormone remain stable with Helicobacter pylori infection: a cross-sectional study |
| title_full_unstemmed | Sperm parameters and anti-Müllerian hormone remain stable with Helicobacter pylori infection: a cross-sectional study |
| title_short | Sperm parameters and anti-Müllerian hormone remain stable with Helicobacter pylori infection: a cross-sectional study |
| title_sort | sperm parameters and anti mullerian hormone remain stable with helicobacter pylori infection a cross sectional study |
| topic | Helicobacter pylori (HP) Anti-müllerian hormone (AMH) Sperm parameters Progressive motility |
| url | http://link.springer.com/article/10.1186/s12894-020-00725-z |
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