SWR1-Independent Association of H2A.Z to the LINC Complex Promotes Meiotic Chromosome Motion

SWR1-Independent Association of H2A.Z to the LINC Complex Promotes Meiotic Chromosome Motion

The H2A.Z histone variant is deposited into the chromatin by the SWR1 complex, affecting multiple aspects of meiosis. We describe here a SWR1-independent localization of H2A.Z at meiotic telomeres and the centrosome. We demonstrate that H2A.Z colocalizes and interacts with Mps3, the SUN component of...

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Bibliographic Details
Main Authors: Sara González-Arranz, Jennifer M. Gardner, Zulin Yu, Neem J. Patel, Jonna Heldrich, Beatriz Santos, Jesús A. Carballo, Sue L. Jaspersen, Andreas Hochwagen, Pedro A. San-Segundo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
meiosis
chromosome movement
LINC complex
H2A.Z
Mps3
Ndj1
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.594092/full

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