Putting the sting back in STING therapy: novel delivery vehicles for improved STING activation

Putting the sting back in STING therapy: novel delivery vehicles for improved STING activation

Engaging the immune sensing Stimulator of Interferon Genes (STING) pathway has emerged as a potentially powerful approach to cancer therapy. However, current STING agonists lack stability and specificity, resulting in toxic adverse effects and disappointing patient outcomes. Therefore, novel deliver...

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Bibliographic Details
Main Authors: Sina Khorsandi, Kristin Huntoon, Jacques Lux
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Chemical Biology
Subjects:
STING
immunotherapy
cancer therapy
drug delivery
particles
Online Access:https://www.frontiersin.org/articles/10.3389/fchbi.2024.1386220/full

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